Multiorgan and Renal Tropism of SARS-CoV-2 In this autopsy series, the authors found that
SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart…

Injury and loss of podocytes are leading factors of glomerular disease and renal failure. The
postmitotic podocyte is the primary glomerular target for toxic, immune, metabolic, and …

Chronic glomerular diseases, associated with renal failure and cardiovascular morbidity,
represent a major health issue. However, they remain poorly understood. Here we have …

Autophagy is responsible for the degradation of protein aggregates and damaged organelles.
Several studies have reported increased autophagic activity in tubular cells after kidney …

Chronic kidney disease (CKD) represents a major health burden 1 . Its central feature of renal
fibrosis is not well understood. By exome sequencing, we identified mutations in FAN1 as …

Predicting renal outcome in antineutrophil cytoplasmic antibody (ANCA)–associated
glomerulonephritis (GN) remains a major challenge. We aimed to identify reliable predictors of end-…

Thrombospondin type 1 domain–containing 7A (THSD7A) is a target antigen identified in adult
membranous nephropathy (MN) along with the major antigen phospholipase A 2 receptor …

Head and neck paragangliomas are tumors arising from specialized neural crest cells.
Prominent locations are the carotid body along with the vagal, jugular, and tympanic glomus. …

Th17 cells are most abundant in the gut, where their presence depends on the intestinal
microbiota. Here, we examined whether intestinal Th17 cells contribute to extra-intestinal Th17 …

The cause of paraneoplastic membranous nephropathy is unclear. In the current case, new
expression of THSD7A in a gallbladder carcinoma and the development of membranous …