User profiles for Thomas Werner

Thomas Werner

Professor, Michigan Technological University
Verified email at mtu.edu
Cited by 3256

Matlnd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

…, K Frech, H Karas, E Wingender, T Werner - Nucleic acids …, 1995 - academic.oup.com
The identification of potential regulatory motifs in new sequence data is increasingly important
for experimental design. Those motifs are commonly located by matches to IUPAC strings …

MatInspector and beyond: promoter analysis based on transcription factor binding sites

…, A Klingenhoff, M Frisch, M Bayerlein, T Werner - …, 2005 - academic.oup.com
Motivation: Promoter analysis is an essential step on the way to identify regulatory networks.
A prerequisite for successful promoter analysis is the prediction of potential transcription …

Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in Drosophila

KM Choe, T Werner, S Stoven, D Hultmark… - Science, 2002 - science.org
Components of microbial cell walls are potent activators of innate immune responses in
animals. For example, the mammalian TLR4 signaling pathway is activated by bacterial …

A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster

T Werner, G Liu, D Kang, S Ekengren… - Proceedings of the …, 2000 - National Acad Sciences
Peptidoglycans from bacterial cell walls trigger immune responses in insects and mammals.
A peptidoglycan recognition protein, PGRP, has been cloned from moths as well as …

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

…, A von Brunn, S Gilch, TF Schwarz, T Werner… - Journal of molecular …, 1999 - Elsevier
Prion diseases are fatal neurodegenerative disorders in man and animal associated with
conformational conversion of a cellular prion protein (PrP c ) into the pathologic isoform (PrP …

Complex learning and information processing by pigeons: A critical analysis

DE Carter, TJ Werner - Journal of the Experimental Analysis of …, 1978 - Wiley Online Library
Three models of conditional discrimination learning by pigeons are described: stimulus
configuration learning, the multiple‐rule model, and concept learning. A review of the literature …

DIALIGN: finding local similarities by multiple sequence alignment.

…, K Frech, A Dress, T Werner - Bioinformatics (Oxford …, 1998 - academic.oup.com
MOTIVATION: DIALIGN is a new method for pairwise as well as multiple alignment of nucleic
acid and protein sequences. While standard alignment programs rely on comparing single …

[HTML][HTML] The regulation and evolution of a genetic switch controlling sexually dimorphic traits in Drosophila

TM Williams, JE Selegue, T Werner, N Gompel, A Kopp… - Cell, 2008 - cell.com
Sexually dimorphic traits play key roles in animal evolution and behavior. Little is known,
however, about the mechanisms governing their development and evolution. One recently …

Multiple DNA and protein sequence alignment based on segment-to-segment comparison.

…, A Dress, T Werner - Proceedings of the …, 1996 - National Acad Sciences
In this paper, a new way to think about, and to construct, pairwise as well as multiple alignments
of DNA and protein sequences is proposed. Rather than forcing alignments to either …

[HTML][HTML] The evolution of gene regulation underlies a morphological difference between two Drosophila sister species

S Jeong, M Rebeiz, P Andolfatto, T Werner, J True… - Cell, 2008 - cell.com
Understanding the mechanisms underlying the morphological divergence of species is one
of the central goals of evolutionary biology. Here, we analyze the genetic and molecular …