Monocytes and macrophages are major components of the tumor microenvironment, but
their contributions to human cancer are poorly understood. We used molecular profiling …

There has been a recent upsurge in worldwide attention on digital pathology, which has
transformed from static snapshots from camera-equipped microscopes to its modern form that …

Glomerulonephritis is a common and debilitating feature of systemic lupus erythematosus (SLE).
The precise immune mechanisms that drive the progression from benign autoimmunity …

PURPOSE: We investigated hypoxia and necrosis in high grade and invasive bladder cancer,
and related this to prognosis. MATERIALS AND METHODS: We performed a retrospective …

Despite its widespread use for prostate cancer screening, low specificity makes PSA a
suboptimal biomarker, especially in the diagnostic “gray zone” of 4–10 ng ml− 1. False-positives …

Background and Purpose: The RENAL Nephrometry Score (RNS) was developed to standardize
the reporting of anatomic information of a renal mass. This study aimed to identify the …

BACKGROUND Nuclear p53 and retinoblastoma protein (pRb) were reported to be poor
prognostic indicators for transitional cell carcinoma of the bladder. The authors sought to …

Objectives To investigate plasma and urinary kynurenine (KYN)–tryptophan (TRP) ratios in
bladder cancer, expression of indoleamine 2,3‐dioxygenase 1 (IDO1) in relation to …

Vitamin D level is linked to susceptibility to infections, but its relevance in candidemia is
unknown. We aimed to investigate the in vivo sequelae of vitamin D 3 supplementation in …

The global increase in autoimmunity, together with the emerging autoimmune-related side
effects of cancer immunotherapy, have furthered a need for understanding of immune …