The burden of neuropathic pain: results from a cross-sectional survey
AM McDermott, TR Toelle, DJ Rowbotham… - European Journal of …, 2006 - Elsevier
BACKGROUND: There are few published data on the treatment patterns and burden of
neuropathic pain. We have investigated this in a large, observational, cross-sectional survey. …
neuropathic pain. We have investigated this in a large, observational, cross-sectional survey. …
[HTML][HTML] App-based multidisciplinary back pain treatment versus combined physiotherapy plus online education: a randomized controlled trial
TR Toelle, DA Utpadel-Fischler, KK Haas… - NPJ digital …, 2019 - nature.com
Non-specific low back pain (LBP) is one of the leading causes of global disability. Multidisciplinary
pain treatment (MPT) programs comprising educational, physical, and psychological …
pain treatment (MPT) programs comprising educational, physical, and psychological …
Digital treatment of back pain versus standard of care: the cluster-randomized controlled trial, Rise-uP
…, J Reichmann, U Marschall, TR Toelle - Journal of pain …, 2020 - Taylor & Francis
Purpose Non-specific low back pain (NLBP) causes an enormous burden to patients and
tremendous costs for health care systems worldwide. Frequently, treatments are not oriented to …
tremendous costs for health care systems worldwide. Frequently, treatments are not oriented to …
[HTML][HTML] Migraine attacks as a result of hypothalamic loss of control
…, V Witkovsky, C Zimmer, E Schulz, TR Toelle - NeuroImage: Clinical, 2021 - Elsevier
Migraine is a complex neurological disorder affecting approximately 12% of the population.
The pathophysiology is not yet fully understood, however the clinical features of the disease, …
The pathophysiology is not yet fully understood, however the clinical features of the disease, …
COMT Val108/158Met genotype affects the mu-opioid receptor system in the human brain: evidence from ligand-binding, G-protein activation and preproenkephalin …
…, A Buettner, B Conrad, M Riemenschneider, TR Toelle - Neuroimage, 2005 - Elsevier
Recent data from [ 11 C]carfentanil ligand-PET indicate that in the human brain, the
availability of mu-opioid (MOP) receptor binding sites is affected by the Val 108/158 Met …
availability of mu-opioid (MOP) receptor binding sites is affected by the Val 108/158 Met …
Less pain, better sleep? The effect of a multidisciplinary back pain app on sleep quality in individuals suffering from back pain–a secondary analysis of app user data
…, D Utpadel-Fischler, TR Toelle - Journal of Pain Research, 2020 - Taylor & Francis
Purpose Mobile health solutions are finding their way into health systems. The Kaia app has
been shown to be able to reduce back pain in two studies. Since pain often comes along …
been shown to be able to reduce back pain in two studies. Since pain often comes along …
[HTML][HTML] Short-term alternating temperature enhances histamine-induced itch: a biphasic stimulus model
F Pfab, M Valet, T Sprenger, TR Toelle… - Journal of investigative …, 2006 - Elsevier
Itch is the major symptom of many allergic or inflammatory skin diseases; yet it is still difficult
to measure objectively. Human studies on the physiology and pathophysiology of the itch …
to measure objectively. Human studies on the physiology and pathophysiology of the itch …
[HTML][HTML] Pregabalin in neuropathic pain related to DPN, cancer and back pain: analysis of a 6-week observational study
TR Toelle, R Varvara, M Nimour, B Emir… - The Open Pain …, 2012 - openpainjournal.com
Background: Neuropathic pain is associated with many conditions. Pregabalin has demonstrated
efficacy in randomized, controlled trials (RCTs) in peripheral and central neuropathic …
efficacy in randomized, controlled trials (RCTs) in peripheral and central neuropathic …
[HTML][HTML] Is there a right control condition in mHealth trials? A critical view on pain medicine
JA Priebe, TR Toelle - npj Digital Medicine, 2019 - nature.com
When mobile health (mHealth) applications (apps) are investigated, the question of the
proper control condition arises. Normally, the randomized controlled trial (RCT) is seen as the …
proper control condition arises. Normally, the randomized controlled trial (RCT) is seen as the …
Quantification of [18F] diprenorphine kinetics in the human brain with compartmental and non-compartmental modeling approaches
…, G Henriksen, K Wagner, HJ Wester, TR Toelle… - Neuroimage, 2004 - Elsevier
6-O-(2-[ 18 F]fluoroethyl)-6-O-desmethyldiprenorphine ([ 18 F]FDPN) is a nonselective opiate
ligand that binds to postsynaptic μ, κ and δ opiate receptors. Due to the longer half-life of F-…
ligand that binds to postsynaptic μ, κ and δ opiate receptors. Due to the longer half-life of F-…