Neutrophil granulocyte derived MMP-9 is a VEGF independent functional component of the angiogenic switch in pancreatic ductal adenocarcinoma
D Bausch, T Pausch, T Krauss, UT Hopt… - Angiogenesis, 2011 - Springer
Background Vascular endothelial growth factor (VEGF) that is secreted by tumor cells plays
a key role in angiogenesis. Matrix metalloproteinase 9 (MMP-9) is produced by inflammatory …
a key role in angiogenesis. Matrix metalloproteinase 9 (MMP-9) is produced by inflammatory …
Cachexia but not obesity worsens the postoperative outcome after pancreatoduodenectomy in pancreatic cancer
T Pausch, W Hartwig, U Hinz, T Swolana, BD Bundy… - Surgery, 2012 - Elsevier
BACKGROUND: Prognosis after pancreatoduodenectomy for pancreatic cancer is determined
by tumor characteristics, completeness of resection, and patient's comorbidity. Our aim …
by tumor characteristics, completeness of resection, and patient's comorbidity. Our aim …
Postoperative pancreatic fistula: we need to redefine grades B and C
T Hackert, U Hinz, T Pausch, I Fesenbeck, O Strobel… - Surgery, 2016 - Elsevier
Background Postoperative pancreatic fistula (POPF) is the most important complication after
pancreatic surgery. In 2005, the International Study Group of Pancreatic Surgery (ISGPS) …
pancreatic surgery. In 2005, the International Study Group of Pancreatic Surgery (ISGPS) …
[HTML][HTML] Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes
TM Pausch, E Aue, NM Wirsik, A Freire Valls, Y Shen… - Scientific Reports, 2020 - nature.com
The characteristic desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a
key contributor to its lethality. This stromal microenvironment is populated by cancer-…
key contributor to its lethality. This stromal microenvironment is populated by cancer-…
[HTML][HTML] Survival benefit of resection surgery for pancreatic ductal adenocarcinoma with liver metastases: a propensity score-matched SEER database analysis
TM Pausch, X Liu, J Cui, J Wei, Y Miao, U Heger… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a devastating illness but guidelines
consider it unresectable once metastasized. However, resection of the primary tumor is …
consider it unresectable once metastasized. However, resection of the primary tumor is …
Static and dynamic 68Ga-FAPI PET/CT for the detection of malignant transformation of intraductal papillary mucinous neoplasia of the pancreas
…, F Bicu, T Hackert, U Heger, T Pausch… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Pancreatic ductal adenocarcinoma (PDAC) may arise from intraductal papillary mucinous
neoplasms (IPMN) with malignant transformation, but a significant portion of IPMN remains to …
neoplasms (IPMN) with malignant transformation, but a significant portion of IPMN remains to …
Fifty years of surgery for pancreatic cancer
T Hackert, U Klaiber, T Pausch, AL Mihaljevic… - Pancreas, 2020 - journals.lww.com
The surgical treatment of pancreatic cancer (PDAC) has seen sweeping changes during the
past 5 decades. Up to the middle of the 20th century resection rates were below 5%, but the …
past 5 decades. Up to the middle of the 20th century resection rates were below 5%, but the …
[HTML][HTML] Myofibroblastic CAF density, not activated stroma index, indicates prognosis after neoadjuvant therapy of pancreatic carcinoma
…, L Schillings, B Walter, D Hartmann, U Hinz, T Pausch… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer is increasingly treated with chemotherapy before
surgery, but this does not improve prognosis for every patient. On a cellular level, pancreatic …
surgery, but this does not improve prognosis for every patient. On a cellular level, pancreatic …
Efficacy of pasireotide for prevention of postoperative pancreatic fistula in pancreatic surgery: a systematic review and meta-analysis
X Liu, T Pausch, P Probst, J Cui, J Wei… - Journal of …, 2020 - Elsevier
Background Pasireotide was recently suggested for the prevention of postoperative pancreatic
fistula (POPF) after pancreatic surgery. However, its efficacy remains to be controversially …
fistula (POPF) after pancreatic surgery. However, its efficacy remains to be controversially …
[HTML][HTML] Next-generation study databases require FAIR, EHR-integrated, and scalable Electronic Data Capture for medical documentation and decision support
…, A Merzweiler, C Niklas, TM Pausch… - NPJ Digital …, 2024 - nature.com
Structured patient data play a key role in all types of clinical research. They are often collected
in study databases for research purposes. In order to describe characteristics of a next-…
in study databases for research purposes. In order to describe characteristics of a next-…