PET-CT image registration in the chest using free-form deformations
…, DR Haynor, H Vesselle, TK Lewellen… - IEEE transactions on …, 2003 - ieeexplore.ieee.org
We have implemented and validated an algorithm for three-dimensional positron emission
tomography transmission-to-computed tomography registration in the chest, using mutual …
tomography transmission-to-computed tomography registration in the chest, using mutual …
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F] fluoromisonidazole: a pretherapy study of 37 patients
…, W Koh, ML Evans, LM Peterson, TK Lewellen… - International Journal of …, 1996 - Elsevier
Purpose: To assess pretreatment hypoxia in a variety of tumors using positron emission
tomography (PET) after injection of the hypoxia-binding radiopharmaceutical [“‘F] …
tomography (PET) after injection of the hypoxia-binding radiopharmaceutical [“‘F] …
Imaging of hypoxia in human tumors with [F-18] fluoromisonidazole
…, JS Rasey, ML Evans, JR Grierson, TK Lewellen… - International Journal of …, 1992 - Elsevier
Fluoromisonidazole (FMISO) has been shown to bind selectively to hypoxic cells in vitro and
in vivo at radiobiologically significant oxygen levels. When labeled with the positron emitter …
in vivo at radiobiologically significant oxygen levels. When labeled with the positron emitter …
Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18] fluoromisonidazole positron emission tomography
…, JR Grierson, KL Lindsley, TK Lewellen… - International Journal of …, 1995 - Elsevier
Purpose : Recent clinical investigations have shown a strong correlation between pretreatment
tumor hypoxia and poor response to radiotherapy. These observations raise questions …
tumor hypoxia and poor response to radiotherapy. These observations raise questions …
18F-FDG PET of gliomas at delayed intervals: improved distinction between tumor and normal gray matter
…, JM Link, TK Lewellen, B Lewellen… - Journal of Nuclear …, 2004 - Soc Nuclear Med
We hypothesized that delineation of gliomas from gray matter with 18 F-FDG PET could be
improved by extending the interval between 18 F-FDG administration and PET data …
improved by extending the interval between 18 F-FDG administration and PET data …
Clinical imaging characteristics of the positron emission mammography camera: PEM Flex Solo II
L MacDonald, J Edwards, T Lewellen… - Journal of Nuclear …, 2009 - Soc Nuclear Med
We evaluated a commercial positron emission mammography (PEM) camera, the PEM Flex
Solo II. This system comprises two 6 × 16.4 cm detectors that scan together covering up to a …
Solo II. This system comprises two 6 × 16.4 cm detectors that scan together covering up to a …
[PDF][PDF] Carbon-11-thymidine and FDG to measure therapy response
…, M Zheng, B Lewellen, TK Lewellen… - Journal of Nuclear …, 1998 - Soc Nuclear Med
MATERIALS AND METhODS Patients We evaluated six patients (6 men; age range 45—
69yr; mean age 60 yr), four with small cell lung cancer and two with sarcomas. Cancer was …
69yr; mean age 60 yr), four with small cell lung cancer and two with sarcomas. Cancer was …
Modeling and incorporation of system response functions in 3-D whole body PET
…, PE Kinahan, TK Lewellen - IEEE transactions on …, 2006 - ieeexplore.ieee.org
Appropriate application of spatially variant system models can correct for degraded resolution
response and mispositioning errors. This paper explores the detector blurring component …
response and mispositioning errors. This paper explores the detector blurring component …
Time-of-flight PET
TK Lewellen - Seminars in nuclear medicine, 1998 - Elsevier
Time-of-Flight (TOF) positron emission tomographs (PET) were developed during the 1980s
and early 1990s. Initial investigations into the potential improvements in signal-to-nolse …
and early 1990s. Initial investigations into the potential improvements in signal-to-nolse …
cMiCE: a high resolution animal PET using continuous LSO with a statistics based positioning scheme
J Joung, RS Miyaoka, TK Lewellen - Nuclear Instruments and Methods in …, 2002 - Elsevier
Objective: Detector designs for small animal scanners are currently dominated by discrete
crystal implementations. However, given the small crystal cross-sections required to obtain …
crystal implementations. However, given the small crystal cross-sections required to obtain …