Prognostic role of platelet to lymphocyte ratio in solid tumors: a systematic review and meta-analysis
…, M Al-Mubarak, FE Vera-Badillo, T Hermanns… - … , biomarkers & prevention, 2014 - AACR
Background: Inflammation influences cancer development and progression. An elevated
platelet to lymphocyte ratio (PLR), a marker of inflammation, has been linked to poor prognosis …
platelet to lymphocyte ratio (PLR), a marker of inflammation, has been linked to poor prognosis …
[HTML][HTML] Automated Gleason grading of prostate cancer tissue microarrays via deep learning
The Gleason grading system remains the most powerful prognostic predictor for patients
with prostate cancer since the 1960s. Its application requires highly-trained pathologists, is …
with prostate cancer since the 1960s. Its application requires highly-trained pathologists, is …
Renal tumor biopsy for small renal masses: a single-center 13-year experience
…, JR Kachura, AJ Evans, AR Zlotta, T Hermanns… - European urology, 2015 - Elsevier
Background Renal tumor biopsy (RTB) for the characterization of small renal masses (SRMs)
has not been widely adopted despite reported safety and accuracy. Without pretreatment …
has not been widely adopted despite reported safety and accuracy. Without pretreatment …
Propensity score analysis of radical cystectomy versus bladder-sparing trimodal therapy in the setting of a multidisciplinary bladder cancer clinic
GS Kulkarni, T Hermanns, Y Wei, B Bhindi… - Journal of clinical …, 2017 - zora.uzh.ch
Purpose Multidisciplinary management improves complex treatment decision making in
cancer care, but its impact for bladder cancer (BC) has not been documented. Although radical …
cancer care, but its impact for bladder cancer (BC) has not been documented. Although radical …
[HTML][HTML] Serum levels of microRNA-371a-3p (M371 test) as a new biomarker of testicular germ cell tumors: results of a prospective multicentric study
…, JF Cremers, C Oing, T Hermanns… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE Previous studies suggested that serum levels of microRNA (miR)-371a-3p (so-called
M371 test) have a much higher sensitivity and specificity than the classic markers of …
M371 test) have a much higher sensitivity and specificity than the classic markers of …
[HTML][HTML] DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
…, JS Dias, D Huntsman, T Hermanns… - The Journal of …, 2019 - Am Soc Clin Investig
Replicative immortality is a hallmark of cancer cells governed by telomere maintenance.
Approximately 90% of human cancers maintain their telomeres by activating telomerase, driven …
Approximately 90% of human cancers maintain their telomeres by activating telomerase, driven …
Change in neutrophil-to-lymphocyte ratio in response to targeted therapy for metastatic renal cell carcinoma as a prognosticator and biomarker of efficacy
…, R Kanesvaran, N Alimohamed, T Hermanns… - European urology, 2016 - Elsevier
Background Neutrophil-to-lymphocyte ratio (NLR), if elevated, is associated with worse
outcomes in several malignancies. Objective Investigation of NLR at baseline and during therapy …
outcomes in several malignancies. Objective Investigation of NLR at baseline and during therapy …
Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma
…, L Von Boehmer, V Cecconi, T Hermanns… - …, 2013 - Taylor & Francis
Although malignant cells can be recognized and controlled by the immune system, in patients
with clinically apparent cancer immunosurveillance has failed. To better understand local …
with clinically apparent cancer immunosurveillance has failed. To better understand local …
[HTML][HTML] FOXA1 promotes tumor progression in prostate cancer and represents a novel hallmark of castration-resistant prostate cancer
…, P Wild, M Beer, F Huber, T Hermanns… - The American journal of …, 2012 - Elsevier
Forkhead box protein A1 (FOXA1) modulates the transactivation of steroid hormone receptors
and thus may influence tumor growth and hormone responsiveness in prostate cancer. We …
and thus may influence tumor growth and hormone responsiveness in prostate cancer. We …
Is there a role for tamsulosin in the treatment of distal ureteral stones of 7 mm or less? Results of a randomised, double-blind, placebo-controlled trial
T Hermanns, P Sauermann, K Rufibach… - European urology, 2009 - Elsevier
BACKGROUND: Numerous randomised trials have confirmed the efficacy of medical
expulsive therapy with tamsulosin in patients with distal ureteral stones; however, to date, no …
expulsive therapy with tamsulosin in patients with distal ureteral stones; however, to date, no …