[HTML][HTML] Importance of beta cell mass for glycaemic control in people with type 1 diabetes

TJP Jansen, M Brom, M Boss, M Buitinga, CJ Tack… - Diabetologia, 2023 - Springer
Aims/hypothesis The role of beta cell mass in the balance of glucose control and
hypoglycaemic burden in people with type 1 diabetes is unclear. We applied positron emission …

Monitoring β-Cell Survival After Intrahepatic Islet Transplantation Using Dynamic Exendin PET Imaging: A Proof-of-Concept Study in Individuals With Type 1 Diabetes

TJP Jansen, M Buitinga, M Boss, MF Nijhoff, M Brom… - Diabetes, 2023 - Am Diabetes Assoc
<p>Intrahepatic transplantation of islets of Langerhans (ITx) is a treatment option for
individuals with complicated type 1 diabetes and profoundly unstable glycemic control, but its …

New Radiolabeled Exendin Analogues Show Reduced Renal Retention

L Joosten, C Frielink, TJP Jansen… - Molecular …, 2023 - ACS Publications
PET imaging of the glucagon-like peptide-1 receptor (GLP-1R) using radiolabeled exendin
is a promising imaging method to detect insulinomas. However, high renal accumulation of …

[PDF][PDF] From mice to men: the exocrine pancreas does not matter for human GLP-1 receptor imaging

M Gotthardt, L Joosten, TJP Jansen… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Non-invasive determination of pancreatic beta cell mass (BCM) in humans is key to understanding
the pathophysiology of Type 1 and 2 Diabetes (T1D, T2D). It appears that BCM and …

Vaccine adjuvant technology: from mechanistic concepts to practical applications

WGJ Degen, T Jansen, VEJC Schijns - Expert Review of Vaccines, 2003 - Taylor & Francis
Distinct types of immune responses are required for efficient elimination of different pathogens.
Programming of the desired type of immune response by safe nonreplicating vaccines …

Structure-and oil type-based efficacy of emulsion adjuvants

T Jansen, MPM Hofmans, MJG Theelen, F Manders… - Vaccine, 2006 - Elsevier
Oil-based emulsions are well-known immunopotentiators for inactivated, “killed” vaccines.
We addressed the relationship between emulsion structure and levels of in vivo antibody …

Structure–activity relations of water-in-oil vaccine formulations and induced antigen-specific antibody responses

T Jansen, MPM Hofmans, MJG Theelen, VEJC Schijns - Vaccine, 2005 - Elsevier
… Author links open overlay panel Theo Jansen a , Marij PM Hofmans b , Marc JG Theelen a ,
… at 1000× magnification (Olympus, model BX50, Japan). The viscosity of the emulsions was …

[PDF][PDF] A proposal of the extended mechanism for theo jansen linkage to modify the walking elliptic orbit and a study of cyclic base function

K Komoda, H Wagatsuma - Proceedings of the 7th Annual Dynamic …, 2012 - ihmc.us
… In the present study, we proposed an extension mechanism of the Theo Jansen linkage to
… , the present study suggests that the Theo Jansen mechanism has a capability to extend an …

Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3

J Kimmel, M Schmitt, A Sinner, PWTC Jansen… - Cell Systems, 2023 - cell.com
Taxon-specific proteins are key determinants defining the biology of all organisms and
represent prime drug targets in pathogens. However, lacking comparability with proteins in other …

Beyond the myth of self-actualization: Reinventing the community perspective of adult education

T Jansen, D Wildemeersch - Adult education quarterly, 1998 - journals.sagepub.com
In this contribution, we discuss two tendencies in mainstream adult and continuing education.
First, there is the tendency to gear adult and continuing education towards individualized …