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[HTML][HTML] Super-resolution spectroscopic microscopy via photon localization
Traditional photon localization microscopy analyses only the spatial distributions of photons
emitted by individual molecules to reconstruct super-resolution optical images. Unfortunately…
emitted by individual molecules to reconstruct super-resolution optical images. Unfortunately…
Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast
…, BE Urban, JE Chandler, TQ Nguyen… - Proceedings of the …, 2016 - National Acad Sciences
Visualizing the nanoscale intracellular structures formed by nucleic acids, such as chromatin,
in nonperturbed, structurally and dynamically complex cellular systems, will help expand …
in nonperturbed, structurally and dynamically complex cellular systems, will help expand …
Nanoscale chromatin imaging and analysis platform bridges 4D chromatin organization with molecular function
Extending across multiple length scales, dynamic chromatin structure is linked to transcription
through the regulation of genome organization. However, no individual technique can fully …
through the regulation of genome organization. However, no individual technique can fully …
[HTML][HTML] Subsurface super-resolution imaging of unstained polymer nanostructures
Optical imaging has offered unique advantages in material researches, such as spectroscopy
and lifetime measurements of deeply embedded materials, which cannot be matched …
and lifetime measurements of deeply embedded materials, which cannot be matched …
[HTML][HTML] Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging
…, A Eid, G Spicer, LM Almassalha, TQ Nguyen… - Light: Science & …, 2019 - nature.com
Optical coherence tomography angiography relies on motion for contrast and requires at
least two data acquisitions per pointwise scanning location. We present a method termed …
least two data acquisitions per pointwise scanning location. We present a method termed …
[HTML][HTML] Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis
…, S Courtade-Gaďani, N Provost, TQ Nguyen… - Nature …, 2023 - nature.com
Systemic sclerosis (SSc) is an autoimmune, inflammatory and fibrotic disease with limited
treatment options. Developing new therapies is therefore crucial to address patient needs. To …
treatment options. Developing new therapies is therefore crucial to address patient needs. To …
Intraoperative Raman spectroscopy of soft tissue sarcomas
Background and Objective Soft tissue sarcomas (STS) are a rare and heterogeneous group
of malignant tumors that are often treated through surgical resection. Current intraoperative …
of malignant tumors that are often treated through surgical resection. Current intraoperative …
Subdiffusion reflectance spectroscopy to measure tissue ultrastructure and microvasculature: model and inverse algorithm
AJ Radosevich, A Eshein, TQ Nguyen… - Journal of biomedical …, 2015 - spiedigitallibrary.org
Reflectance measurements acquired from within the subdiffusion regime (ie, lengthscales
smaller than a transport mean free path) retain much of the original information about the …
smaller than a transport mean free path) retain much of the original information about the …
Rectal Optical Markers for In Vivo Risk Stratification of Premalignant Colorectal Lesions
AJ Radosevich, NN Mutyal, A Eshein, TQ Nguyen… - Clinical Cancer …, 2015 - AACR
Purpose: Colorectal cancer remains the second leading cause of cancer deaths in the United
States despite being eminently preventable by colonoscopy via removal of premalignant …
States despite being eminently preventable by colonoscopy via removal of premalignant …
[HTML][HTML] Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain
TQ Nguyen, M Chenon, F Vilela, C Velours… - PloS one, 2017 - journals.plos.org
Kinesin1 plays a major role in neuronal transport by recruiting many different cargos
through its kinesin light chain (KLC). Various structurally unrelated cargos interact with the …
through its kinesin light chain (KLC). Various structurally unrelated cargos interact with the …