Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems. Molecular …

A novel Pt(II) terpyridine complex that has a nicotinamide moiety linked to the terpyridyl ligand
has been synthesized in good yield and studied structurally and spectroscopically. The …

Photoinduced charge separation is a fundamental step in photochemical energy conversion.
In the design of molecularly based systems for light-to-chemical energy conversion, this …

We report our initial investigations into the use of tetraazamacrocycles as zirconium-89
chelators. We describe the synthesis and complete characterization of several Zr …

The interest in zirconium-89 ( 89 Zr) as a positron-emitting radionuclide has grown considerably
over the last decade due to its standardized production, long half-life of 78.2 h, favorable …

Targeted alpha-particle therapy (TAT) aims to selectively deliver radionuclides emitting α-particles
(cytotoxic payload) to tumors by chelation to monoclonal antibodies, peptides or small …

OBJECTIVES: The α v β 3 integrin is a cell adhesion molecule known to be involved in stages
of angiogenesis and metastasis. In this study, the chelators CB-TE2A and diamsar were …

The theranostic potential of 225 Ac-based radiopharmaceuticals continues to increase as
researchers seek innovative ways to harness the nuclear decay of this radioisotope for …

The number of radiopharmaceuticals containing copper radionuclides for diagnostic
imaging and targeted radiotherapy has grown considerably over the past few decades. This …

OBJECTIVE. A significant challenge facing traditional cancer therapies is their propensity to
significantly harm normal tissue. The recent clinical success of targeting therapies by …