User profiles for Tetsuji Miura

Tetsuji Miura

Sapporo Medical University, Hokkaido University of Science
Verified email at sapmed.ac.jp
Cited by 28166

[HTML][HTML] Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

M Tanno, J Sakamoto, T Miura, K Shimamoto… - Journal of Biological …, 2007 - ASBMB
Sir2 (silent information regulator 2) is an NAD + -dependent histone deacetylase that
contributes to longevity in yeast. SIRT1, a mammalian Sir2 ortholog, deacetylates histones and …

[HTML][HTML] Diabetic cardiomyopathy: pathophysiology and clinical features

T Miki, S Yuda, H Kouzu, T Miura - Heart failure reviews, 2013 - Springer
Since diabetic cardiomyopathy was first reported four decades ago, substantial information
on its pathogenesis and clinical features has accumulated. In the heart, diabetes enhances …

Fatty acid-binding protein 4 (FABP4): pathophysiological insights and potent clinical biomarker of metabolic and cardiovascular diseases

…, S Saitoh, K Shimamoto, T Miura - Clinical Medicine …, 2014 - journals.sagepub.com
Over the past decade, evidences of an integration of metabolic and inflammatory pathways,
referred to as metaflammation in several aspects of metabolic syndrome, have been …

[HTML][HTML] Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure

M Tanno, A Kuno, T Yano, T Miura, S Hisahara… - Journal of Biological …, 2010 - ASBMB
Oxidative stress plays a pivotal role in chronic heart failure. SIRT1, an NAD + -dependent
histone/protein deacetylase, promotes cell survival under oxidative stress when it is expressed …

[HTML][HTML] Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

…, R Kharbanda, S Lecour, M Marber, T Miura… - Basic research in …, 2016 - Springer
To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers
in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the …

Urinary angiotensin-converting enzyme 2 in hypertensive patients may be increased by olmesartan, an angiotensin II receptor blocker

…, S Saitoh, N Ura, K Shimamoto, T Miura - American journal of …, 2015 - academic.oup.com
BACKGROUND Angiotensin-converting enzyme 2 (ACE2) is highly expressed in the kidney
and converts angiotensin (Ang) II to Ang-(1–7), a renoprotective peptide. Urinary ACE2 has …

Strain rate imaging for noninvasive functional quantification of the left atrium: comparative studies in controls and patients with atrial fibrillation

…, K Uno, T Nakata, K Tsuchihashi, T Miura… - Journal of the American …, 2005 - Elsevier
Strain rate (SR) imaging enables quantitative measurement of left ventricular (LV) function
independent of cardiac translation. However, whether SR imaging is applicable for detection …

Modulation of the mitochondrial permeability transition pore complex in GSK-3β-mediated myocardial protection

M Nishihara, T Miura, T Miki, M Tanno, T Yano… - Journal of molecular and …, 2007 - Elsevier
Recently we found that the level of anti-infarct tolerance afforded by ischemic preconditioning
(IPC) and erythropoietin (EPO) infusion was closely correlated with the level of Ser9-…

[HTML][HTML] Predominant expression of Sir2α, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain

J Sakamoto, T Miura, K Shimamoto, Y Horio - FEBS letters, 2004 - Elsevier
Sir2 is an NAD-dependent histone deacetylase that functions in longevity, gene silencing,
heterochromatin formation, DNA repair, and suppression of DNA recombination in yeast. The …

Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapy

T Miura, T Miki - Basic research in cardiology, 2008 - Springer
This review takes a critical look at the current effectiveness of reperfusion therapy for acute
myocardial infarction and at the potential for cardioprotective agents to improve it. …