First-in-humans evaluation of a PD-L1–binding peptide PET radiotracer in non–small cell lung cancer patients

X Zhou, J Jiang, X Yang, T Liu, J Ding… - Journal of Nuclear …, 2022 - Soc Nuclear Med
68 Ga-NOTA-WL12 is a peptide-based PET imaging agent. We conducted a first-in-human
study of 68 Ga-NOTA-WL12 for PET to study the in vivo biodistribution, metabolism, radiation …

68Ga-PSMA-617 PET/CT: a promising new technique for predicting risk stratification and metastatic risk of prostate cancer patients

C Liu, T Liu, N Zhang, Y Liu, N Li, P Du, Y Yang… - European journal of …, 2018 - Springer
Purpose The purpose of this study was to investigate the performance of 68 Ga-PSMA-617
PET/CT in predicting risk stratification and metastatic risk of prostate cancer. Methods Fifty …

A highly specific multiple enhancement theranostic nanoprobe for PET/MRI/PAI image‐guided radioisotope combined photothermal therapy in prostate cancer

L Xia, X Meng, L Wen, N Zhou, T Liu, X Xu, F Wang… - Small, 2021 - Wiley Online Library
An integrated molecular probe for combined tumor‐targeted multimodal imaging and therapy
in the era of precision medicine requires a multiplexed platform that simultaneously has …

68Ga-PSMA PET/CT combined with PET/ultrasound-guided prostate biopsy can diagnose clinically significant prostate cancer in men with previous negative biopsy …

C Liu, T Liu, Z Zhang, N Zhang, P Du… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The purpose of this study was to investigate the feasibility and diagnostic efficacy of 68 Ga-prostate-specific
membrane antigen (PSMA) PET/CT combined with PET/ultrasound-guided …

Preclinical evaluation and pilot clinical study of Al18F-PSMA-BCH for prostate cancer PET imaging

T Liu, C Liu, X Xu, F Liu, X Guo, N Li… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA)–targeted radioligands have played an
important role in the diagnosis of prostate cancer. In this study, we developed an Al 18 F-labeled …

[HTML][HTML] Dynamic PET/CT Imaging of 68Ga-FAPI-04 in Chinese Subjects

S Wang, X Zhou, X Xu, J Ding, T Liu, J Jiang… - Frontiers in …, 2021 - frontiersin.org
This study aims to further explore dynamic 68 Ga-FAPI-04 PET/CT imaging of healthy Chinese
subjects and lung cancer patients. Moreover, the variability of 68 Ga-FAPI-04 uptake in …

Molecular PET/CT profiling of ACE2 expression in vivo: implications for infection and outcome from SARS‐CoV‐2

…, N Zhou, J Ding, J Jiang, T Liu, Z Liu… - Advanced …, 2021 - Wiley Online Library
Rapid progress has been made to identify and study the causative agent leading to coronavirus
disease 2019 (COVID‐19) but many questions including who is most susceptible and …

Synthesis, preclinical evaluation, and a pilot clinical imaging study of [18F]AlF-NOTA-JR11 for neuroendocrine neoplasms compared with [68Ga]Ga-DOTA-TATE

Q Xie, T Liu, J Ding, N Zhou, X Meng, H Zhu… - European Journal of …, 2021 - Springer
Purpose A [ 18 F]AlF-labeled somatostatin receptor (SSTR) antagonist was developed for
imaging of neuroendocrine neoplasms (NENs), evaluated and compared with [ 68 Ga]Ga-…

Unique role of molecular imaging probes for viral infection

S Liu, T Liu, W Tian, Q Zhang, Z Wang, X Hou… - TrAC Trends in …, 2023 - Elsevier
In recent years, several epidemics, such as COVID-19 and other viral infections, have been
attacking human health and affecting the economy. Non-invasively detecting virus entry into …

[HTML][HTML] Construction of 124I-trastuzumab for noninvasive PET imaging of HER2 expression: from patient-derived xenograft models to gastric cancer patients

X Guo, N Zhou, Z Chen, T Liu, X Xu, X Lei, L Shen… - Gastric Cancer, 2020 - Springer
Purpose Here, we sought to develop a PET radioligand based on trastuzumab labeled with
124 I, 124 I-trastuzumab, to evaluate its distribution, internal dosimetry, and initial PET …