Angiotensin -converting enzyme 2 (ACE2) is a regulator of the renin angiotensin system
involved in acute lung failure, cardiovascular functions and severe acute respiratory syndrome (…

Near complete reabsorption of filtered amino acids is a main specialized transport function
of the kidney proximal tubule. This evolutionary conserved task is carried out by a subset of …

Mutations in the main intestinal and kidney luminal neutral amino acid transporter B 0 AT1 (Slc6a19)
lead to Hartnup disorder, a condition that is characterized by neutral aminoaciduria …

System L amino acid transport is increased in various types of cancer. The tracer 123 I-2-iodotyrosine
(2IT), which is accumulated via system L, could thus serve to allow visualization of …

Levodopa (L-DOPA) is the naturally occurring precursor amino acid for dopamine and the
main therapeutic agent for neurologic disorders due to dopamine depletion, such as Parkinson…

… Tamara Ramadan… Tamara Ramadan… of small intestine enterocytes and the sinusoidal
membrane of perivenous hepatocytes (Ramadan et al. 2006). The analysis of tat1 mRNA …

Basolateral efflux is a necessary step in transepithelial (re)absorption of amino acids from
small intestine and kidney proximal tubule. The best characterized basolateral amino acid …

▪ Abstract Reabsorption of amino acids, similar to that of glucose, is a major task of the
proximal kidney tubule. Various amino acids are actively transported across the luminal brush …

Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis
has not been addressed. Here we show using different types of genetically modified mice …

The rate of amino acid efflux from individual cells needs to be adapted to cellular demands
and plays a central role for the control of extracellular amino acid homeostasis. A particular …