User profiles for Takeshi Nakano
Takeshi NakanoRIKEN, Japan Verified email at riken.go.jp Cited by 4727 |
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
…, Y Fukata, M Nakafuku, B Yamamori, J Feng, T Nakano… - Science, 1996 - science.org
The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation,
which results in contraction of smooth muscle and interaction of actin and myosin in …
which results in contraction of smooth muscle and interaction of actin and myosin in …
[HTML][HTML] Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
…, M Ito, K Kimura, Y Fukata, K Chihara, T Nakano… - Journal of Biological …, 1996 - ASBMB
The small GTPase Rho is implicated in physiological functions associated with actin-myosin
filaments such as cytokinesis, cell motility, and smooth muscle contraction. We have recently …
filaments such as cytokinesis, cell motility, and smooth muscle contraction. We have recently …
Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.
…, K Chihara, M Nakafuku, M Ito, T Nakano… - The EMBO …, 1996 - embopress.org
The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular
signals such as lysophosphatidic acid to form stress fibers and focal contacts. Here we have …
signals such as lysophosphatidic acid to form stress fibers and focal contacts. Here we have …
Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death
…, Y Hayasaki, Y Tsutomi, K Akahane, T Nakano… - Oncogene, 2000 - nature.com
Caspase 3 is an essential death factor for the Fas-mediated cell death, and its inactivation
in cells is initiated by an interaction with p21 on mitochondria or with IAP family member ILP. …
in cells is initiated by an interaction with p21 on mitochondria or with IAP family member ILP. …
[PDF][PDF] Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis
Plant steroid hormones, brassinosteroids (BRs), are perceived by a cell surface receptor
kinase, BRI1, but how BR binding leads to regulation of gene expression in the nucleus is …
kinase, BRI1, but how BR binding leads to regulation of gene expression in the nucleus is …
The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access
We analyzed global gene expression in Arabidopsis in response to various hormones and in
related experiments as part of the AtGenExpress project. The experimental agents included …
related experiments as part of the AtGenExpress project. The experimental agents included …
Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone
…, M Hiroe, S Morimoto, S Hiramitsu, T Nakano… - The American journal of …, 2001 - Elsevier
Cardiac involvement is an important prognostic factor in sarcoidosis, but reliable indicators
of mortality risk in cardiac sarcoidosis are unstudied in a large number of patients. To …
of mortality risk in cardiac sarcoidosis are unstudied in a large number of patients. To …
[HTML][HTML] Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
…, M Amano, K Kimura, H Kanaide, T Nakano… - Journal of Biological …, 1997 - ASBMB
Small GTPase Rho plays pivotal roles in the Ca 2+ sensitization of smooth muscle. However,
the GTP-bound active form of Rho failed to exert Ca 2+ -sensitizing effects in extensively …
the GTP-bound active form of Rho failed to exert Ca 2+ -sensitizing effects in extensively …
Survivin promotes cell proliferation in human hepatocellular carcinoma
…, M Moriyama, H Kawano, M Hayashida, T Nakano… - Hepatology, 2000 - journals.lww.com
Survivin is a recently described inhibitor of apoptosis. Because suppression of apoptosis is
important for carcinogenesis and tumor growth, we investigated the expression and function …
important for carcinogenesis and tumor growth, we investigated the expression and function …
[HTML][HTML] Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase
…, M Nishikawa, DJ Hartshorne, T Nakano - Journal of Biological …, 1999 - ASBMB
It is clear from several studies that myosin phosphatase (MP) can be inhibited via a pathway
that involves RhoA. However, the mechanism of inhibition is not established. These studies …
that involves RhoA. However, the mechanism of inhibition is not established. These studies …