User profiles for Takeshi Nakano

Takeshi Nakano

RIKEN, Japan
Verified email at riken.go.jp
Cited by 4727

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

…, Y Fukata, M Nakafuku, B Yamamori, J Feng, T Nakano… - Science, 1996 - science.org
The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation,
which results in contraction of smooth muscle and interaction of actin and myosin in …

[HTML][HTML] Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

…, M Ito, K Kimura, Y Fukata, K Chihara, T Nakano… - Journal of Biological …, 1996 - ASBMB
The small GTPase Rho is implicated in physiological functions associated with actin-myosin
filaments such as cytokinesis, cell motility, and smooth muscle contraction. We have recently …

Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

…, K Chihara, M Nakafuku, M Ito, T Nakano… - The EMBO …, 1996 - embopress.org
The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular
signals such as lysophosphatidic acid to form stress fibers and focal contacts. Here we have …

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

…, Y Hayasaki, Y Tsutomi, K Akahane, T Nakano… - Oncogene, 2000 - nature.com
Caspase 3 is an essential death factor for the Fas-mediated cell death, and its inactivation
in cells is initiated by an interaction with p21 on mitochondria or with IAP family member ILP. …

[PDF][PDF] Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis

ZY Wang, T Nakano, J Gendron, J He, M Chen… - Developmental cell, 2002 - cell.com
Plant steroid hormones, brassinosteroids (BRs), are perceived by a cell surface receptor
kinase, BRI1, but how BR binding leads to regulation of gene expression in the nucleus is …

The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access

…, S Takatsuto, S Fujioka, T Asami, T Nakano… - The Plant …, 2008 - Wiley Online Library
We analyzed global gene expression in Arabidopsis in response to various hormones and in
related experiments as part of the AtGenExpress project. The experimental agents included …

Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone

…, M Hiroe, S Morimoto, S Hiramitsu, T Nakano… - The American journal of …, 2001 - Elsevier
Cardiac involvement is an important prognostic factor in sarcoidosis, but reliable indicators
of mortality risk in cardiac sarcoidosis are unstudied in a large number of patients. To …

[HTML][HTML] Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

…, M Amano, K Kimura, H Kanaide, T Nakano… - Journal of Biological …, 1997 - ASBMB
Small GTPase Rho plays pivotal roles in the Ca 2+ sensitization of smooth muscle. However,
the GTP-bound active form of Rho failed to exert Ca 2+ -sensitizing effects in extensively …

Survivin promotes cell proliferation in human hepatocellular carcinoma

…, M Moriyama, H Kawano, M Hayashida, T Nakano… - Hepatology, 2000 - journals.lww.com
Survivin is a recently described inhibitor of apoptosis. Because suppression of apoptosis is
important for carcinogenesis and tumor growth, we investigated the expression and function …

[HTML][HTML] Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase

…, M Nishikawa, DJ Hartshorne, T Nakano - Journal of Biological …, 1999 - ASBMB
It is clear from several studies that myosin phosphatase (MP) can be inhibited via a pathway
that involves RhoA. However, the mechanism of inhibition is not established. These studies …