Experimental models for evaluation of radioactive tumor-localizing agents

TP Haynie, T Konikowski, HJ Glenn - Seminars in Nuclear Medicine, 1976 - Elsevier
Although subject to limitations, there is a need for carefully controlled laboratory studies
using animal tumor models in research on tumor-localizing agents. This paper reviews the …

[PDF][PDF] Brain tumor-scanning agents compared in an animal model

T Konikowski, MF Jahns, TP Haynie… - Journal of Nuclear …, 1975 - Soc Nuclear Med
MATERIALSANDMETHODS Radiopharmaceuticals for the diagnostic delinea tion of tumors
have been selected rather empirically based on availability of radionuclide and chemical …

[PDF][PDF] The effect of perchlorate on the localization of 99mTc-pertechnetate in a mouse brain sarcoma

T Konikowski, TP Haynie - Journal of Nuclear Medicine, 1970 - Soc Nuclear Med
MATERIALSANDMETHODS Tedmedum-99m. Technetium-99m-pertechnetate was obtained
commercially in a ready-to-inject form (Pertechtin, Hastings Radiochemicals Works, Hous …

[PDF][PDF] The kinetics of 99mTc-, 113mIn-, and 169Yb-DTPA compounds in brain sarcoma and kidneys of mice

TP Haynie, T Konikowski, HJ Glenn - Journal of Nuclear Medicine, 1972 - Soc Nuclear Med
Ytterbium-169-DTPA chelate (Yb-DTPA) was obtained as an investigational drug (Minnesota
Min ing and Manufacturing Co., St. Paul, Minn.). The specific activity was 0.2 mCi/mi (0.255 …

[PDF][PDF] Technetium-99m stannous citrate brain-tumor uptake in mice: Concise communication

TP Haynie, T Konikowski, HJ Glenn - Journal of Nuclear Medicine, 1977 - Soc Nuclear Med
… Haynie,Tad Konikowski,and Howard J. Glenn … FARR LE, KONIKOWSKI T: The effect of
regional … KoNIKowsKI T, GLENN HJ, HAYNIE TP : Renal clear …

Kinetics of 111In-bleomycin and 111 In-chlorides in mice.

T Konikowski, TP Haynie, HJ Glenn - Journal of Nuclear Medicine …, 1975 - europepmc.org
Indium-111 as the chloride and chelated to bleomycin has been reported useful as a tumor-scanning
agent. This report of the kinetics of these compounds compared in Yale-Swiss mice …

Leukocyte labeling with technetium-99m

…, N Ruksawin, TP Haynie, T Konikowski - International Journal of …, 1976 - Elsevier
Erythrocyte labeling with 51 Cr or 99m Tc is a well-established procedure in nuclear medicine.
The labeled cells are useful in the measurement of red cell mass, in erythrocyte survival …

Long range effects of neutron capture therapy of cancer in mice—I Correlation between the time of intracellular residence of 10B Na pentaborate and the …

LE Farr, T Konikowski - International Journal of Nuclear Medicine and …, 1976 - Elsevier
In 1587 mice, each bearing a potentially lethal neoplasm implanted in the right thigh, the
tumoricidal effects of a single exposure to a standard thermal neutron fluence, ranging from …

Differences in 111In uptake in mouse brain sarcoma based on form of administration

T Konikowski, HJ Glenn, TP Haynie… - International Journal of …, 1977 - Elsevier
It has been shown that when 111 In is injected as the chloride, it largely binds to transferrin.
We studied the biokinetics and distribution of three substances in mice bearing an in situ …

Long range effects of neutron capture therapy of cancer in mice II. Dose effect

LE Farr, T Konikowski - International Journal of Nuclear Medicine and …, 1978 - Elsevier
An index is established which compares the outcome of neutron therapy experiments when
only a single exposure is given to a transplantable malignant neoplasm in mice if the thermal …