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Hypoxia positron emission tomography imaging with 18F-fluoromisonidazole

ST Lee, AM Scott - Seminars in nuclear medicine, 2007 - Elsevier
The importance of hypoxia in disease pathogenesis and prognosis is gathering increasing
clinical significance and having a greater impact on patient management and outcome. …

The value of 18F-FDG PET/CT for predicting or monitoring immunotherapy response in patients with metastatic melanoma: a systematic review and meta-analysis

N Ayati, R Sadeghi, Z Kiamanesh, ST Lee… - European journal of …, 2021 - Springer
The value of 18F-FDG PET/CT for predicting or monitoring immunotherapy response in patients
with metastatic melanoma: a systematic review and meta-analysis | European Journal of …

Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective …

…, R Shakher, LM Wong, K Taubman, ST Lee… - The Lancet, 2020 - thelancet.com
Background Conventional imaging using CT and bone scan has insufficient sensitivity
when staging men with high-risk localised prostate cancer. We aimed to investigate whether …

[HTML][HTML] Radiolabeled antibodies for cancer imaging and therapy

S Parakh, ST Lee, HK Gan, AM Scott - Cancers, 2022 - mdpi.com
Simple Summary Monoclonal antibodies (mAbs) have the ability to specifically target tumor-cell
antigens. This unique property has led to their use in the delivery of radioisotopes to …

[177Lu] Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial

…, NK Rutherford, A Weickhardt, AM Scott, ST Lee… - The Lancet, 2021 - thelancet.com
Background Lutetium-177 [ 177 Lu]Lu-PSMA-617 is a radiolabelled small molecule that delivers
β radiation to cells expressing prostate-specific membrane antigen (PSMA), with activity …

PSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu] Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate …

…, RJ Francis, AY Zhang, AM Scott, ST Lee… - The Lancet …, 2022 - thelancet.com
Background Previously, results from the TheraP trial showed that treatment with lutetium-177
[ 177 Lu]Lu-PSMA-617 improved frequency of prostate-specific antigen (PSA) response …

Visual assessment versus quantitative assessment of 11C-PIB PET and 18F-FDG PET for detection of Alzheimer's disease

…, VL Villemagne, S Berlangieri, ST Lee… - Journal of nuclear …, 2007 - Soc Nuclear Med
Amyloid-β (Aβ) imaging with N-methyl- 11 C-2-(4′-methylamino-phenyl)-6-hydroxy-benzothiazole
( 11 C-6-OH-BTA-1; also known as 11 C-PIB) shows a robust increase in cortical …

High Impact of 18F-FDG-PET on Management and Prognostic Stratification of Newly Diagnosed Small Cell Lung Cancer

A Azad, F Chionh, AM Scott, ST Lee… - Molecular imaging and …, 2010 - Springer
Purpose We evaluated whether 18 F-FDG-PET altered stage classification, management,
and prognostic stratification of newly diagnosed small cell lung cancer (SCLC). Procedures …

Hypoxia-targeted radiotherapy dose painting for head and neck cancer using 18F-FMISO PET: A biological modeling study

…, M Wada, NJ Anderson, D Lim Joon, ST Lee… - Acta …, 2013 - Taylor & Francis
Background. This study investigates the use of 18 F-fluoromisonidazole (FMISO) PET-guided
radiotherapy dose painting for potentially overcoming the radioresistant effects of hypoxia …

Immune priming with avelumab and rituximab prior to R-CHOP in diffuse large B-cell lymphoma: the phase II AvR-CHOP study

K Manos, G Chong, C Keane, ST Lee, C Smith… - Leukemia, 2023 - nature.com
Immune evasion, due to abnormal expression of programmed-death ligands 1 and 2 (PD-L1/PD-L2),
predicts poor outcomes with chemoimmunotherapy in diffuse large B-cell …
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