Prostate cancer consists of secretory cells and a population of immature cells. The function
of immature cells and their mutual relation with secretory cells are still poorly understood. …

Purpose Prostate-specific antigen (PSA)-based screening for prostate cancer (PC) has
dramatically increased early diagnosis. Current imaging techniques are not optimal to stage early …

Human prostate cancers (PC) overexpress gastrin-releasing peptide (GRP) receptors. This
observation suggests that GRP receptors may be used as new visualization and treatment …

Purpose Prostate cancer (PC) is a major health problem. Overexpression of the gastrin-releasing
peptide receptor (GRPR) in PC, but not in the hyperplastic prostate, provides a …

Human prostate cancer (PC) overexpresses the gastrin‐releasing peptide receptor (GRPR).
Radiolabeled GRPR‐targeting analogs of bombesin (BN) have successfully been …

This study describes a novel xenograft-based biomarker discovery platform and proves its
usefulness in the discovery of serum markers for prostate cancer. By immunizing immuno-…

A panel of cytokine-secreting RM-9 prostate cancer cells were tested as whole cell vaccines
to determine their capacity to evoke an anti-prostate cancer immune response. In our model, …

Purpose Radiolabelled peptides used for peptide receptor radionuclide therapy are excreted
mainly via the kidneys and are partly reabsorbed and retained in the proximal tubular cells. …

… Hein van der Poel for the ASO hybridization, and Denie Zonruiter and Suzanne
Reneman for biotechnical assistance in the animal care and propagation of the xenografts. …

Vascularization is still one of the most important limitations for the survival of engineered
tissues after implantation. In this study, we aim to improve the in vivo vascularization of …