Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: assessment of cell survival, engraftment, and distribution …
…, JR Ghadri, MY Emmert, E Müller, SM Küest, S Cohrs… - Circulation, 2012 - Am Heart Assoc
Background— Evaluation of novel cellular therapies in large-animal models and patients is
currently hampered by the lack of imaging approaches that allow for long-term monitoring of …
currently hampered by the lack of imaging approaches that allow for long-term monitoring of …
The low-energy β− and electron emitter 161Tb as an alternative to 177Lu for targeted radionuclide therapy
S Lehenberger, C Barkhausen, S Cohrs… - Nuclear medicine and …, 2011 - Elsevier
INTRODUCTION: The low-energy β − emitter 161 Tb is very similar to 177 Lu with respect to
half-life, beta energy and chemical properties. However, 161 Tb also emits a significant …
half-life, beta energy and chemical properties. However, 161 Tb also emits a significant …
Future prospects for SPECT imaging using the radiolanthanide terbium-155—production and preclinical evaluation in tumor-bearing mice
…, U Köster, H Dorrer, J Reber, S Haller, S Cohrs… - Nuclear medicine and …, 2014 - Elsevier
Introduction We assessed the suitability of the radiolanthanide 155 Tb (t 1/2 = 5.32 days, E γ
= 87 keV (32%), 105 keV (25%)) in combination with variable tumor targeted biomolecules …
= 87 keV (32%), 105 keV (25%)) in combination with variable tumor targeted biomolecules …
[HTML][HTML] Folate receptor-positive gynecological cancer cells: in vitro and in vivo characterization
The folate receptor alpha (FR) is expressed in a variety of gynecological cancer types. It has
been widely used for tumor targeting with folic acid conjugates of diagnostic and therapeutic …
been widely used for tumor targeting with folic acid conjugates of diagnostic and therapeutic …
Anti-L1CAM radioimmunotherapy is more effective with the radiolanthanide terbium-161 compared to lutetium-177 in an ovarian cancer model
J Grünberg, D Lindenblatt, H Dorrer, S Cohrs… - European journal of …, 2014 - Springer
Purpose The L1 cell adhesion molecule (L1CAM) is considered a valuable target for
therapeutic intervention in different types of cancer. Recent studies have shown that anti-L1CAM …
therapeutic intervention in different types of cancer. Recent studies have shown that anti-L1CAM …
Copper-67 Radioimmunotherapy and growth inhibition by anti–L1-cell adhesion molecule monoclonal antibodies in a therapy model of ovarian Cancer metastasis
K Knogler, J Grünberg, K Zimmermann, S Cohrs… - Clinical Cancer …, 2007 - AACR
Purpose: We examined the tumor-targeting and therapeutic effects of 67 Cu-labeled single
amino acid mutant forms of anti-L1 monoclonal antibody chCE7 in nude mice with …
amino acid mutant forms of anti-L1 monoclonal antibody chCE7 in nude mice with …
[HTML][HTML] Simultaneous Visualization of 161Tb- and 177Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging
F Borgna, P Barritt, PV Grundler, Z Talip, S Cohrs… - Pharmaceutics, 2021 - mdpi.com
The decay of terbium-161 results in the emission of β-particles as well as conversion and
Auger electrons, which makes terbium-161 interesting for therapeutic purposes. The aim of this …
Auger electrons, which makes terbium-161 interesting for therapeutic purposes. The aim of this …
[HTML][HTML] 18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease—A Proof-of-Concept Study
…, M Benešová, M Brunner, S Haller, S Cohrs… - Frontiers in …, 2019 - frontiersin.org
Background: Interstitial lung disease (ILD) is a common and severe complication in rheumatic
diseases. Folate receptor-β is expressed on activated, but not resting macrophages which …
diseases. Folate receptor-β is expressed on activated, but not resting macrophages which …
[HTML][HTML] Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model
P Guzik, K Siwowska, HY Fang, S Cohrs… - European journal of …, 2021 - Springer
Purpose It was previously demonstrated that radiation effects can enhance the therapy
outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model …
outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model …
The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor
A Friedli, E Fischer, I Novak-Hofer, S Cohrs… - The international journal …, 2009 - Elsevier
A soluble form of the L1 cell adhesion molecule (sL1) is released from various tumor cells
and can be found in serum and ascites fluid of uterine and ovarian carcinoma patients. sL1 is …
and can be found in serum and ascites fluid of uterine and ovarian carcinoma patients. sL1 is …