Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain

…, CT Christoffersen, S Timmermann… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Phosphodiesterase 10A (PDE10A) plays a key role in the regulation of brain striatal signaling,
and several pharmaceutical companies currently investigate PDE10A inhibitors in clinical …

Patient-specific modeling of the neuroendocrine HPA-axis and its relation to depression: Ultradian and circadian oscillations

J Gudmand-Hoeyer, S Timmermann… - Mathematical …, 2014 - Elsevier
In the Western world approximately 10% of the population experience severe depression at
least once in their lifetime and many more experience a mild form of depression. Depression …

[HTML][HTML] Novel characteristics of valveless pumping

S Timmermann, JT Ottesen - Physics of Fluids, 2009 - pubs.aip.org
This study investigates the occurrence of valveless pumping in a fluid-filled system consisting
of two open tanks connected by an elastic tube. We show that directional flow can be …

Population pharmacokinetics of brodalumab in patients with moderate to severe plaque psoriasis

S Timmermann, A Hall - Basic & Clinical Pharmacology & …, 2019 - Wiley Online Library
Brodalumab is a fully human monoclonal antibody targeting the IL‐17 receptor A leading to
an inhibition of the biological effect of IL‐17A, IL‐17F, IL‐17A/F heterodimer, IL‐17C and IL‐…

Population Pharmacokinetics of Tralokinumab in Adult Subjects With Moderate to Severe Atopic Dermatitis

…, MS Larsen, S Timmermann - Clinical Pharmacology in …, 2022 - Wiley Online Library
Tralokinumab is the first biologic therapy for moderate‐to‐severe atopic dermatitis (AD) that
specifically neutralizes interleukin‐13 activity, a key driver of AD signs and symptoms. …

[PDF][PDF] Matematisk modellering af væskestrømningen i elastisk forbundne kar med periodisk sammenpresning

S Timmermann - Institut for Studiet af Matematik og Fysik samt …, 2005 - forskning.ruc.dk
Roskilde University Page 1 Roskilde University Matematisk modellering af væskestrømningen
i elastisk forbundne kar med periodisk sammenpresning Timmermann, Stine Published in…

[PDF][PDF] Undergraduates' solving strategies and teachers' practice

S Timmermann - C. Winsløw (éd.), Didactics of Mathematics–the French …, 2005 - ind.ku.dk
This paper discusses the possibility of using the Anthropological Theory of Didactics to analyse
the possible relationship between how the teacher conducts his teaching and the solving …

[PDF][PDF] Kursusundervisning og løsningsprocesser i universitetsmatematik: En kamp mellem" stort" og" småt"

S Timmermann - MONA-Matematik-og Naturfagsdidaktik, 2007 - tidsskrift.dk
Resumé På videregående universitetskurser i matematik bruger studenter en stor del af
tiden på at prøve at

[PDF][PDF] Reviewing textbook proofs in class: A struggle between proof structure, components and details

S Timmermann - Proceedings of the Fifth Congress of the …, 2007 - researchgate.net
During the first year of a university study in mathematics,“dissection” of mathematical proofs
occupy a growing part of the course time. In this paper I investigate how we can describe, …

Sabril Vision Study: Pharmacokinetic and Pharmacodynamic Analysis of the Effect of Vigabatrin on Taurine Plasma Concentrations (P2. 026)

D Tolbert, S Timmermann, J Areberb, D Lee… - Neurology, 2016 - AAN Enterprises
Objective: Explore the relationship between vigabatrin plasma concentrations and (1) vision
endpoints (Humphrey field analyzer [HFA] and retinal nerve fiber layer [RNFL]), and (2) …