Background— Delivery of inappropriate shocks caused by misdetection of supraventricular
tachycardia (SVT) remains a substantial complication of implanted cardioverter/defibrillator (…

There is conflicting data concerning the effects of cardiac hypertrophy and failure on L-type
Ca 2+ channel density, the amplitude of the intracellular Ca 2+ transients, and the …

Background— Substrate-guided ablation of ventricular tachycardia (VT) in patients with
implanted cardioverter-defibrillators (ICDs) relies on voltage mapping to define the scar and …

Cardiac atrial cells lack a regular system of transverse tubules like that in cardiac ventricular
cells. Nevertheless, many atrial cells do possess an irregular internal transverse‐axial …

To investigate the cellular mechanisms for altered Ca 2+ homeostasis and contractility in
cardiac hypertrophy, we measured whole-cell L-type Ca 2+ currents (I Ca,L ), whole-cell Ca 2+ …

Objectives : This study sought to assess the feasibility of deriving 3-dimensional (3D) scar
maps from positron emission tomography (PET)/computed tomography (CT) hybrid imaging …

Background— T-wave alternans (TWA) is an important noninvasive measure of ventricular
arrhythmia vulnerability. This study tested the hypothesis that the autonomic nervous system …

Background— Advances in contrast-enhanced multidetector CT enable detailed characterization
of the left ventricular myocardium. Myocardial scar and border zone (BZ), as the target …

OBJECTIVES.: The aim of this study was to compare complications in a large cohort of
patients undergoing pectoral cardioverterdefibrillator implantation with a subcutaneous or …

Background— Innervation is a critical component of arrhythmogenesis and may present an
important trigger/substrate modifier not used in current ventricular tachycardia (VT) ablation …