Quantification of F2-isoprostanes as a biomarker of oxidative stress

GL Milne, SC Sanchez, ES Musiek, JD Morrow - Nature protocols, 2007 - nature.com
Oxidant stress has been implicated in a wide variety of disease processes. One method to
quantify oxidative injury is to measure lipid peroxidation. Quantification of a group of …

N‐acetylcysteine targets 5 lipoxygenase‐derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following …

…, JT Pinto, V Darley‐Usmar, S Sanchez… - Annals of …, 2018 - Wiley Online Library
Objectives N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox modulatory
compound currently in trials for many neurological and psychiatric disorders. Although …

Quantification of F2‐isoprostanes in biological fluids and tissues as a measure of oxidant stress

GL Milne, H Yin, JD Brooks, S Sanchez… - Methods in …, 2007 - Elsevier
Oxidant stress has been implicated in a wide variety of disease processes. One method to
quantify oxidative injury is to measure lipid peroxidation. Quantification of a group of …

Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 …

LJ Murphey, MK Williams, SC Sanchez, LM Byrne… - Analytical …, 2004 - Elsevier
Prostaglandin (PG)E 2 is a major cyclooxygenase (COX) product that is important in human
physiology and pathophysiology. Quantification of systemic PG production in humans is best …

Peripheral F2‐isoprostanes and F4‐neuroprostanes are not increased in Alzheimer's disease

…, D Milatovic, LC Silbert, T Dang, S Sanchez… - Annals of …, 2002 - Wiley Online Library
Quantitative biomarkers of oxidative damage, such as the F 2 ‐isoprostanes (IsoPs) and F 4
‐neuroprostanes (F 4 ‐NeuroPs), may be useful in assessing progression and response to …

The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation

…, CJ BRAME, J YANG, SC SANCHEZ… - Drug Metabolism …, 1999 - Taylor & Francis
Free radicals, largely derived from oxygen, have been implicated in the pathophysiology of
many human diseases, including cancer, atherosclerosis, neurodegenerative disorders, and …

Measurement of F2-isoprostanes and isofurans using gas chromatography–mass spectrometry

…, B Gao, ES Terry, WE Zackert, SC Sanchez - Free Radical Biology and …, 2013 - Elsevier
F 2 -Isoprostanes (IsoPs) are isomers of prostaglandin F 2α formed from the nonenzymatic
free radical-catalyzed peroxidation of arachidonic acid. Since discovery of these molecules by …

Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor

…, L Brou, C Carnevale, SC Sanchez… - Obstetrics & …, 2011 - journals.lww.com
OBJECTIVE: To evaluate amniotic fluid arachidonic acid metabolites using enzymatic and
nonenzymatic (lipid peroxidation) pathways in spontaneous preterm birth and term births, and …

Unsupervised classification in hyperspectral imagery with nonlocal total variation and primal-dual hybrid gradient algorithm

W Zhu, V Chayes, A Tiard, S Sanchez… - … on Geoscience and …, 2017 - ieeexplore.ieee.org
In this paper, a graph-based nonlocal total variation method is proposed for unsupervised
classification of hyperspectral images (HSI). The variational problem is solved by the primal-…

Cognitive impairment in children with CACNA1A mutations

…, F Rivier, A de Saint Martin, S Sanchez… - … Medicine & Child …, 2020 - Wiley Online Library
Aim To describe the clinico‐radiological phenotype of children with a CACNA 1A mutation
and to precisely evaluate their learning ability and cognitive status. Method Children between …