User profiles for Stefan Stangl

Stefan Stangl

Dr. rer. nat., Technische Universität München
Verified email at tum.de
Cited by 2619

CD 8+ tumour‐infiltrating lymphocytes in relation to HPV status and clinical outcome in patients with head and neck cancer after postoperative chemoradiotherapy: A …

…, J Debus, C Bayer, S Stangl… - … journal of cancer, 2016 - Wiley Online Library
We examined the prognostic value of tumour‐infiltrating lymphocytes (TILs) in patients with
squamous cell carcinoma of the head and neck (SCCHN) after surgery and postoperative …

[HTML][HTML] Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

S Tzoumas, A Nunes, I Olefir, S Stangl… - Nature …, 2016 - nature.com
Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent
fluence attenuation, an effect that causes spectral corruption. Spectral corruption …

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70. 1 antibody

S Stangl, M Gehrmann, J Riegger… - Proceedings of the …, 2011 - National Acad Sciences
Immunization of mice with a 14-mer peptide TKDNNLLGRFELSG, termed “TKD,” comprising
amino acids 450–461 (aa 450–461 ) in the C terminus of inducible Hsp70, resulted in the …

The PD‐1/PD‐L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: a multicentre study of the German Cancer …

…, A Abdollahi, J Debus, S Stangl… - … journal of cancer, 2017 - Wiley Online Library
We examined the prognostic role of PD‐1+ and CD8+ tumor infiltrating lymphocytes (TILs),
and PD‐L1+ cells in patients with squamous cell carcinoma of the head and neck (SCCHN) …

[HTML][HTML] Correlation of Hsp70 serum levels with gross tumor volume and composition of lymphocyte subpopulations in patients with squamous cell and adeno non …

S Gunther, C Ostheimer, S Stangl, HM Specht… - Frontiers in …, 2015 - frontiersin.org
Heat-shock protein 70 (Hsp70) is frequently found on the plasma membrane of a large number
of malignant tumors including non-small cell lung cancer (NSCLC) and gets released into …

[HTML][HTML] Hsp70-a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck

…, M Sedelmayr, D Schilling, W Sievert, S Stangl… - Radiation …, 2014 - Springer
Background Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70)
and present it on their cell surface (mHsp70) from where it can be actively released. …

[HTML][HTML] Role of membrane Hsp70 in radiation sensitivity of tumor cells

N Murakami, A Kühnel, TE Schmid, K Ilicic, S Stangl… - Radiation …, 2015 - Springer
Background The major stress-inducible heat shock protein 70 (Hsp70) is frequently
overexpressed in the cytosol and integrated in the plasma membrane of tumor cells via lipid …

Targeted natural killer cell–based adoptive immunotherapy for the treatment of patients with NSCLC after radiochemotherapy: a randomized phase II clinical trial

G Multhoff, S Seier, S Stangl, W Sievert… - Clinical Cancer …, 2020 - AACR
Purpose: Non–small cell lung cancer (NSCLC) is a fatal disease with poor prognosis. A
membrane-bound form of Hsp70 (mHsp70) which is selectively expressed on high-risk tumors …

Heat shock protein 70 and tumor‐infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy …

S Stangl, N Tontcheva, W Sievert… - … journal of cancer, 2018 - Wiley Online Library
Tumor cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their
cell surface, where it can be recognized by pre‐activated NK cells. In our retrospective study …

[HTML][HTML] Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung …

M Shevtsov, E Pitkin, A Ischenko, S Stangl… - Frontiers in …, 2019 - frontiersin.org
Heat shock protein 70 (Hsp70) which is expressed on the plasma membrane of highly
aggressive tumors including non-small cell lung carcinoma and glioblastoma multiforme serves …