This study investigated cerebral glucose metabolism in very early Alzheimer's disease,
before a clinical diagnosis of probable Alzheimer's disease is possible, using [ 18 F]…

Objective. —To evaluate the efficacy and safety of high-dose tacrine hydrochloride over 30
weeks in patients with probable Alzheimer's disease. Design. —A 30-week randomized, …

Patients with chronic hypercortisolemia due to Cushing's syndrome (CS) exhibit cognitive
dysfunction. Because glucocorticoid excess is associated with hippocampal damage in …

The disruptive behavior of persons with dementia is a problem of considerable clinical
interest and growing scientific concern. This paper offers a view of these behaviors as …

Objective. —To compare efficacy and safety of tacrine hydrochloride with placebo in
patients with probable Alzheimer's disease. Design. —A 12-week, double-blind, placebo-controlled, …

Background: Decreased hippocampal volume is observed in patients with Cushing’s syndrome
and other conditions associated with elevated cortisol levels, stress, or both. Reversibility …

Background Some elderly individuals exhibit significant memory deficits but do not have
dementia because their general intellect is preserved and they have no impairments in …

Fifteen drug‐free patients with early to midstage Huntington's disease were evaluated with
quantitative neurological examinations, scales for functional capacity, computed tomographic …

Frontal, limbic and temporal regions of the brain important in emotion perception and executive
functioning also have been implicated in the etiology and maintenance of depression; yet…

In an extension of previous work, we studied the behavioral correlates of medial frontal lobe
glucose hypometabolism in chronically alcohol‐dependent patients. Thirty‐one male …