Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States.
Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to …

Idiopathic pulmonary fibrosis (IPF) is a lethal disease with an average life expectancy of 3 to
5 years. IPF is characterized by progressive stiffening of the lung parenchyma due to …

Tumor-targeted fluorescent dyes have been shown to significantly improve a surgeon's
ability to locate and resect occult malignant lesions, thereby enhancing a patient's chances of …

Fibroblast activation protein (FAP) has received increasing attention as an oncologic target
because of its prominent expression in solid tumors but virtual absence from healthy tissues. …

For any drug candidate to be approved by the US Food and Drug Administration, it must
meet strict standards for safety and efficacy. While the field of nuclear medicine is over 100 …

Currently, oncology testing includes molecular studies and cytogenetic analysis to detect
genetic aberrations of clinical significance. Next-generation sequencing (NGS) allows rapid …

With the development of accurate and precise techniques for quantifying sodium, potassium,
calcium, and magnesium concentrations, a vast literature has been generated indicating …

The role of Notch signaling in the maintenance of adult murine prostate epithelial homeostasis
remains unclear. We found that Notch ligands are mainly expressed within the basal cell …

Objective: To review the range of promising technologies (eg, smart phones, remote monitoring
devices) designed to enhance aging in place; identify challenges for implementation of …

Background: Glioblastoma multiforme (GBM) continues to devastate patients and outfox
investigators and clinicians despite the preponderance of research directed at its biology, …