User profiles for Sonali Darbar

Sonali (Darbar) Munshaw

University of Oxford
Verified email at dpag.ox.ac.uk
Cited by 233

Imaging DNA Damage In Vivo Using γH2AX-Targeted Immunoconjugates

B Cornelissen, V Kersemans, S Darbar, J Thompson… - Cancer research, 2011 - AACR
DNA damage responses (DDR) occur during oncogenesis and therapeutic responses to DNA
damaging cytotoxic drugs. Thus, a real-time method to image DNA damage in vivo would …

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical

B Cornelissen, S Darbar, V Kersemans, D Allen… - Nuclear medicine and …, 2012 - Elsevier
111 In-DTPA-anti-γH2AX-Tat, which combines an anti-γH2AX antibody with a cell-penetrating
peptide, Tat, and the Auger electron-emitting radioisotope, 111 In, targets the DNA …

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance 111In-DTPA-hEGF Auger …

B Cornelissen, S Darbar, R Hernandez… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The intracellular distribution of Auger electron–emitting radiopharmaceuticals is a determinant
of cytotoxicity. However, the mechanisms by which these agents are routed through the …

Amplification of IR-induced DNA damage by Auger electron treatment with TAT-radioimmunoconjugates

B Cornelissen, S Darbar, K Sleeth, V Kersemans… - 2009 - Soc Nuclear Med
638 Objectives The most deleterious DNA lesions caused by ionizing radiation are double
strand breaks (DSB). We hypothesise that it is possible to amplify DSB damage using a novel …

Molecular radiation therapy: Targeting DNA damage response proteins

C Bart, V Kersemans, S Darbar, S Smart, KA Vallis - Cancer research, 2010 - AACR
DNA damage is an early event after exposure of cells to many anti-cancer agents. Auger
electron-emitting radiopharmaceuticals that localize at sites of DNA-double strand breaks (dsb) …

Imaging of DNA double strand breaks in vivo using fluorophore-labelled TAT-immunoconjugates

B Cornelissen, V Kersemans, K Sleeth, S Darbar… - 2009 - Soc Nuclear Med
1015 Objectives DNA double strand breaks (DSB) are the most deleterious lesion caused
by ionizing radiation (IR). Following DSB formation, the histone, H2AX, is phosphorylated by …

Intracellular trafficking of 111In-DTPA-EGF is altered by co-administration of molecularly targeted anticancer agents and influences cell kill by Auger electrons

B Cornelissen, S Darbar, J Mitchell, I Tullis, B Vojnovic… - 2009 - Soc Nuclear Med
1562 Objectives The intracellular distribution of Auger-electron emitting radiopharmaceuticals
is an important determinant of cytotoxicity. The mechanisms by which these agents are …

Effectiveness and safety of salmeterol/fluticasone fixed-dose combination delivered through Synchrobreathe® in patients with asthma: the real-world EVOLVE study

…, L Meena, S Sandesh, J Sonali… - Therapeutic …, 2022 - journals.sagepub.com
Background: Inhalation therapy with corticosteroids and long-acting β 2 -agonists has been
the mainstay of asthma management. However, choosing the correct inhaler technique is …

[PDF][PDF] MOYNA COLLEGE

N Accredited - History, 2017 - moynacollege.ac.in
SONALI KUNDU … 3840.00 100 MOY2310726 MCUG23101161 SONALI KUNDU …
3650.00 101 MOY2310396 MCUG23100634 SONALI BARMAN …

Quantitative, Noninvasive Imaging of DNA Damage in Vivo of Prostate Cancer Therapy by Transurethral Photoacoustic (TUPA) Imaging

L Xiang, Stanford University Stanford United States - 2015 - apps.dtic.mil
The first year of this research program developed the foundation for a new medical imaging
modality, now called Trans-Urethral Photoacoustic TUPA Imaging, which utilizing a small …