The serotonergic system and in particular serotonin 1A receptor (5-HT1AR) are implicated in
major depressive disorder (MDD). Here we demonstrated that 5-HT1AR is palmitoylated in …

Evidence suggests that certain taxonomic groups are more thoroughly studied than others
across a wide range of biological disciplines. Such taxonomic biases have the potential to …

When sound stimulates the stereocilia on the sensory cells in the hearing organ, Ca 2+ ions
flow through mechanically gated ion channels. This Ca 2+ influx is thought to be important …

Background Prostate-specific membrane antigen (PSMA) targeting radioligands have
transformed treatment of prostate cancer. Radioligand therapy (RLT) with 177 Lu-PSMA in …

Surgery with curative intent can be offered to congenital hyperinsulinism (CHI) patients,
provided that the lesion is focal. Radiolabeled exendin-4 specifically binds the glucagonlike …

Protein–protein interaction is often investigated using quantitative molecular microscopy
with Förster resonant energy transfer (FRET). Here, we combined ‘linear unmixing FRET’ (lux-…

Single channel electrophysiological studies have been carried out to elucidate the underlying
interactions during the translocation of polypeptides through protein channels. For this we …

Peptide receptor radionuclide therapy (PRRT) using radiolabeled somatostatin receptor (SSTR)
analogs is a common approach in advanced neuroendocrine neoplasms. Recently, …

Paper industry uses huge amount of freshwater during different steps of the papermaking
process, and discharge highly contaminated toxic effluent in the environment. The paper and …

Background: Molecular targeting remains to be a promising approach in oncology.
Overexpression of G protein-coupled receptors (GPCRs) in human cancer is offering a powerful …