Role of renal microcirculation in experimental renovascular disease

R Iliescu, SR Fernandez, S Kelsen… - Nephrology Dialysis …, 2010 - academic.oup.com
Background. Renal artery stenosis (RAS) causes renal injury partly via microvascular (MV)
endothelial dysfunction and damage. Vascular endothelial growth factor (VEGF) is crucial for …

Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice

…, A Jurkuvenaite, S Fernandez… - American Journal of …, 2011 - atsjournals.org
Chlorine (Cl 2 ) gas exposure poses an environmental and occupational hazard that frequently
results in acute lung injury. There is no effective treatment. We assessed the efficacy of …

Sc-HOPO: A Potential Construct for Use in Radioscandium-Based Radiopharmaceuticals

…, GE Lopez, S Saini, CC Parker, SR Fernandez… - Inorganic …, 2023 - ACS Publications
Three isotopes of scandium─ 43 Sc, 44 Sc, and 47 Sc─have attracted increasing attention
as potential candidates for use in imaging and therapy, respectively, as well as for possible …

Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer

…, AVF Massicano, AG Sorace, S Fernandez… - Molecular …, 2023 - ACS Publications
Tumor-associated macrophages (TAMs) are large phagocytic cells that play numerous roles
in cancer biology and are an important component of the relationship between immune …

Optimized methods for production and purification of Titanium-45

IF Chaple, K Thiele, G Thaggard, S Fernandez… - Applied Radiation and …, 2020 - Elsevier
Titanium-45 (t 1/2 = 3.08 h) is a radiometal with excellent nuclear characteristics, including a
high positron branching ratio (85%) and low average positron energy (0.439 MeV), for the …

Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation

…, SF Doran, GL Squadrito, S Fernandez… - American Journal of …, 2012 - atsjournals.org
We assessed the safety and efficacy of combined intravenous and aerosolized antioxidant
administration to attenuate chlorine gas–induced airway alterations when administered after …

Augmented endothelial‐specific L‐arginine transport prevents obesity‐induced hypertension

…, F Karim, NE Straznicky, S Fernandez… - Acta …, 2014 - Wiley Online Library
Aim Hypertension is a major clinical complication of obesity. Our previous studies show that
abnormal uptake of the nitric oxide precursor L ‐arginine, via the cationic amino acid …

[HTML][HTML] New 55Co-labeled Albumin-Binding Folate Derivatives as Potential PET Agents for Folate Receptor Imaging

LL Radford, S Fernandez, R Beacham, R El Sayed… - Pharmaceuticals, 2019 - mdpi.com
Overexpression of folate receptors (FRs) on different tumor types (eg, ovarian, lung) make
FRs attractive in vivo targets for directed diagnostic/therapeutic agents. Currently, no …

Comparative Uptake and Biological Distribution of [18F]-Labeled C6 and C8 Perfluorinated Alkyl Substances in Pregnant Mice via Different Routes of Administration

JL Bartels, SR Fernandez, TA Aweda… - … & Technology Letters, 2020 - ACS Publications
Elevated blood sera concentrations of perfluorinated and polyfluorinated alkyl substances (PFAS)
are associated with many adverse human health effects, including lower birth weight …

[HTML][HTML] In vivo Assessment of the Impact of Molecular Weight on Constructs of 68Ga-DOTA-Manocept in a Syngeneic Mouse Tumor Model

JL Bartels, SR Fernandez, JS Arnold, CC Parker… - Molecular Imaging and …, 2023 - Springer
Purpose Manocept™ constructs are mannosylated amine dextrans (MADs) that bind with high
affinity to the mannose receptor, CD206. Tumor-associated macrophages (TAMs) are the …