Baseline PET radiomics outperforms the IPI risk score for prediction of outcome in diffuse large B-cell lymphoma

…, MW Heymans, S Pieplenbosch… - Blood, The Journal …, 2023 - ashpublications.org
The objective of this study is to externally validate the clinical positron emission tomography
(PET) model developed in the HOVON-84 trial and to compare the model performance of …

[HTML][HTML] Quantitative implications of the updated EARL 2019 PET–CT performance standards

A Kaalep, CN Burggraaff, S Pieplenbosch, EE Verwer… - EJNMMI physics, 2019 - Springer
Purpose Recently, updated EARL specifications (EARL2) have been developed and
announced. This study aims at investigating the impact of the EARL2 specifications on the …

[HTML][HTML] Optimizing workflows for fast and reliable metabolic tumor volume measurements in diffuse large B cell lymphoma

…, F Rahman, I Kaßner, S Pieplenbosch… - Molecular Imaging and …, 2020 - Springer
Purpose This pilot study aimed to determine interobserver reliability and ease of use of three
workflows for measuring metabolic tumor volume (MTV) and total lesion glycolysis (TLG) in …

[HTML][HTML] An artificial intelligence method using FDG PET to predict treatment outcome in diffuse large B cell lymphoma patients

…, SE Wiegers, GJC Zwezerijnen, S Pieplenbosch… - Scientific Reports, 2023 - nature.com
Convolutional neural networks (CNNs) may improve response prediction in diffuse large B-cell
lymphoma (DLBCL). The aim of this study was to investigate the feasibility of a CNN …

Baseline radiomics features and MYC rearrangement status predict progression in aggressive B-cell lymphoma

…, SE Wiegers, S Pieplenbosch… - Blood …, 2023 - ashpublications.org
We investigated whether the outcome prediction of patients with aggressive B-cell lymphoma
can be improved by combining clinical, molecular genotype, and radiomics features. MYC, …

[HTML][HTML] Combatting the effect of image reconstruction settings on lymphoma [18F]FDG PET metabolic tumor volume assessment using various segmentation …

…, SE Wiegers, GJC Zwezerijnen, S Pieplenbosch… - EJNMMI research, 2022 - Springer
Background [ 18 F]FDG PET-based metabolic tumor volume (MTV) is a promising prognostic
marker for lymphoma patients. The aim of this study is to assess the sensitivity of several …

18F-FDG PET improves baseline clinical predictors of response in diffuse large B-cell lymphoma: The HOVON-84 study

…, SE Wiegers, S Pieplenbosch… - Journal of Nuclear …, 2022 - Soc Nuclear Med
We aimed to determine the added value of baseline metabolic tumor volume (MTV) and
interim PET (I-PET) to the age-adjusted international prognostic index (aaIPI) to predict 2-y …

Plausibility and redundancy analysis to select FDG‐PET textural features in non‐small cell lung cancer

…, L Mesotten, I Zhovannik, S Pieplenbosch… - Medical …, 2021 - Wiley Online Library
Background Radiomics refers to the extraction of a large number of image biomarker describing
the tumor phenotype displayed in a medical image. Extracted from positron emission …

Interobserver agreement on automated metabolic tumor volume measurements of deauville score 4 and 5 Lesions at Interim 18F-FDG PET in diffuse large B-Cell …

…, EAIN Shaban, S Pieplenbosch… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Metabolic tumor volume (MTV) on interim PET (I-PET) is a potential prognostic biomarker for
diffuse large B-cell lymphoma (DLBCL). Implementation of MTV on I-PET requires a …

[HTML][HTML] Interobserver reproducibility of tumor uptake quantification with 89Zr-immuno-PET: a multicenter analysis

…, OS Hoekstra, JM Zijlstra, S Pieplenbosch… - European journal of …, 2019 - Springer
Purpose In-vivo quantification of tumor uptake of 89-zirconium ( 89 Zr)-labelled monoclonal
antibodies (mAbs) with PET provides a potential tool in strategies to optimize tumor targeting …