User profiles for Shinn-Zong Lin

Shinn-Zong Lin, MD, Ph.D., CPI

Professor of Neurosurgery, Hualien Tzu Chi Medical Center
Verified email at tzuchi.com.tw
Cited by 20744

Mesenchymal stem cells

DC Ding, WC Shyu, SZ Lin - Cell transplantation, 2011 - journals.sagepub.com
Stem cells have two features: the ability to differentiate along different lineages and the ability
of self-renewal. Two major types of stem cells have been described, namely, embryonic …

Functional recovery of stroke rats induced by granulocyte colony-stimulating factor–stimulated stem cells

WC Shyu, SZ Lin, HI Yang, YS Tzeng, CY Pang… - Circulation, 2004 - Am Heart Assoc
Background— Stroke is a leading cause of death and disability worldwide; however, no
effective treatment currently exists. Methods and Results— Rats receiving subcutaneous …

Enhancement of neuroplasticity through upregulation of β1-integrin in human umbilical cord-derived stromal cell implanted stroke model

DC Ding, WC Shyu, MF Chiang, SZ Lin, YC Chang… - Neurobiology of …, 2007 - Elsevier
Neuroplasticity subsequent to functional angiogenesis is an important goal for cell-based
therapy of ischemic neural tissues. At present, the cellular and molecular mechanisms involved …

Intracerebral peripheral blood stem cell (CD34+) implantation induces neuroplasticity by enhancing β1 integrin-mediated angiogenesis in chronic stroke rats

WC Shyu, SZ Lin, MF Chiang, CY Su… - Journal of …, 2006 - Soc Neuroscience
Although stem cell-based treatments for stroke and other neurodegenerative diseases have
advanced rapidly, there are still few clinical treatments available. In this study, rats receiving …

Transplantation of human Wharton's Jelly-derived stem cells alleviates chemically induced liver fibrosis in rats

SZ Lin, YJ Chang, JW Liu, LF Chang… - Cell …, 2010 - journals.sagepub.com
There is currently no effective treatment method available for liver fibrosis. We therefore
evaluated the use of Wharton's jelly stem cells (WJSCs; the major umbilical cord stem cell …

Intracerebral implantation of autologous peripheral blood stem cells in stroke patients: a randomized phase II study

…, SZ Lin, JR Fan, CH Lin, W Lee, CC Lin… - Cell …, 2014 - journals.sagepub.com
In our previous study, intracerebral implantation of peripheral blood stem cells (PBSCs)
improved functional outcome in rats with chronic cerebral infarction. Based on this finding, a …

Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy

DC Ding, YH Chang, WC Shyu, SZ Lin - Cell transplantation, 2015 - journals.sagepub.com
The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs).
Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster …

Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts

TM Lee, NC Chang, SZ Lin - Free Radical Biology and Medicine, 2017 - Elsevier
During myocardial infarction, infiltrated macrophages have pivotal roles in cardiac remodeling
and delayed M1 toward M2 macrophage phenotype transition is considered one of the …

Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex

Y Wang, SZ Lin, AL Chiou, LR Williams… - Journal of …, 1997 - Soc Neuroscience
Glial cell line-derived neurotrophic factor (GDNF), a recently described and cloned member
of the transforming growth factor (TGF)-β superfamily, has been shown to have marked …

Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial

WC Shyu, SZ Lin, CC Lee, DD Liu, H Li - Cmaj, 2006 - Can Med Assoc
… by Shinn-Zong Lin and Hung Li. Woei-Cherng Shyu, Hung Li and Shinn-Zong Lin were …
Shinn-Zong Lin, Chau-Chin Lee and Hung Li drafted the manuscript. All of the authors …