Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)

…, K Dezaki, J Wang, S Morishima - The Journal of …, 2001 - Wiley Online Library
A fundamental property of animal cells is the ability to regulate their own cell volume. Even
under hypotonic stress imposed by either decreased extracellular or increased intracellular …

Volume‐sensitive chloride channels in mouse cortical neurons: Characterization and role in volume regulation

H Inoue, S Mori, S Morishima… - European Journal of …, 2005 - Wiley Online Library
Because persistent swelling causes cell damage and often results in cell death, volume
regulation is an important physiological function in both neuronal and non‐neuronal cells. Brain …

IK channels are involved in the regulatory volume decrease in human epithelial cells

J Wang, S Morishima, Y Okada - American Journal of …, 2003 - journals.physiology.org
Parallel activation of Ca 2+ -dependent K + channels and volume-sensitive Cl − channels is
known to be responsible for KCl efflux during regulatory volume decrease (RVD) in human …

Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction

…, RZ Sabirov, H Liu, S Mori, S Morishima - Current Topics in …, 2019 - Elsevier
Two types of anion channels are directly activated by osmotic swelling and are involved in the
regulatory volume decrease (RVD) in most types of mammalian cells, and they include the …

Molecular Cloning, Water Channel Activity and Tissue Specific Expression of Two Isoforms of Radish Vacuolar Aquaporin1

…, T Tsuchiya, H Hisada, S Morishima… - Plant and cell …, 1998 - academic.oup.com
A major membrane intrinsic protein (VM23) in vacuoles of radish (Raphanus) tap root was
investigated. The cDNAs for two isoforms of VM23, γ- and δ-VM23, encode polypeptides of …

Two-photon excitation fluorescence imaging of the living juxtaglomerular apparatus

J Peti-Peterdi, S Morishima, PD Bell… - American Journal of …, 2002 - journals.physiology.org
Recently, multiphoton excitation fluorescence microscopy has been developed that offers
important advantages over confocal imaging, particularly for in vivo visualization of thick tissue …

ClC-3-independent, PKC-dependent Activity of Volume-sensitive Cl- Channel in Mouse Ventricular Cardiomyocytes

W Gong, H Xu, T Shimizu, S Morishima… - Cellular Physiology and …, 2004 - karger.com
Volume-sensitive outwardly rectifying (VSOR) Cl - channels are activated during osmotic
swelling and involved in the subsequent volume regulation in most animal cells. To test the …

Phloretin differentially inhibits volume‐sensitive and cyclic AMP‐activated, but not Ca‐activated, Cl channels

HT Fan, S Morishima, H Kida… - British journal of …, 2001 - Wiley Online Library
Some phenol derivatives are known to block volume‐sensitive Cl − channels. However,
effects on the channel of the bisphenol phloretin, which is a known blocker of glucose uniport …

[HTML][HTML] Snapin, a new regulator of receptor signaling, augments α1A-adrenoceptor-operated calcium influx through TRPC6

F Suzuki, S Morishima, T Tanaka… - Journal of biological …, 2007 - ASBMB
Activation of G q -protein-coupled receptors, including the α 1A -adrenoceptor (α 1A -AR),
causes a sustained Ca 2+ influx via receptor-operated Ca 2+ (ROC) channels, following the …

Identification of α-1L and α-1A adrenoceptors in human prostate by tissue segment binding

S Morishima, T Tanaka, H Yamamoto, F Suzuki… - The Journal of …, 2007 - Elsevier
PURPOSE: Silodosin (KMD-3213 or [(-)-1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide])
(Kissei …