User profiles for Sheryl Roberts

Sheryl Roberts

Assistant Professor, Wayne State University
Verified email at wayne.edu
Cited by 628

High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies

…, L Agemy, M Omar, A Berezhnoi, S Roberts… - Nature biomedical …, 2020 - nature.com
The monitoring of vascular-targeted therapies using magnetic resonance imaging, computed
tomography or ultrasound is limited by their insufficient spatial resolution. Here, by taking …

Calcium sensor for photoacoustic imaging

S Roberts, M Seeger, Y Jiang, A Mishra… - Journal of the …, 2018 - ACS Publications
We introduce a selective and cell-permeable calcium sensor for photoacoustics (CaSPA), a
versatile imaging technique that allows for fast volumetric mapping of photoabsorbing …

Optical imaging modalities: principles and applications in preclinical research and clinical settings

G Pirovano, S Roberts, S Kossatz… - Journal of Nuclear …, 2020 - Soc Nuclear Med
With the ability to noninvasively image and monitor molecular processes within tumors,
molecular imaging represents a fundamental tool for cancer scientists. In the current review, we …

Safety and Feasibility of PARP1/2 Imaging with 18F-PARPi in Patients with Head and Neck Cancer

…, PDDS França, R Nakajima, E Burnazi, S Roberts… - Clinical Cancer …, 2020 - AACR
Purpose: We performed a first-in-human clinical trial. The aim of this study was to determine
safety and feasibility of PET imaging with 18 F-PARPi in patients with head and neck cancer. …

Near-infrared photoacoustic imaging probe responsive to calcium

A Mishra, Y Jiang, S Roberts, V Ntziachristos… - Analytical …, 2016 - ACS Publications
Photoacoustic imaging (PAI) is an attractive imaging modality that can volumetrically map the
distribution of photoabsorbing molecules with deeper tissue penetration than multiphoton …

PARP-targeted Auger therapy in p53 mutant colon cancer xenograft mouse models

…, G Pirovano, G Xiao, Z Samuels, S Roberts… - Molecular …, 2021 - ACS Publications
Despite Auger electrons being highly appealing due to their short-range and high linear
energy transfer to surrounding tissues, the progress in the field has been limited due to the …

A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer

…, C Brand, D Karassawa Zanoni, S Roberts… - European journal of …, 2021 - Springer
Background Visual inspection and biopsy is the current standard of care for oral cancer
diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically applied …

Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine …

BE Mc Larney, M Kim, S Roberts… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Shortwave infrared (900–1,700 nm) fluorescence imaging (SWIRFI) has shown significant
advantages over visible (400–650 nm) and near-infrared (700–900 nm) fluorescence imaging …

[HTML][HTML] Fluorescence-guided resection of tumors in mouse models of oral cancer

P Demetrio de Souza Franca, N Guru, S Roberts… - Scientific reports, 2020 - nature.com
Complete removal and negative margins are the goal of any surgical resection of primary
oral cavity carcinoma. Current approaches to determine tumor boundaries rely heavily on …

Preclinical and first-in-human-brain-cancer applications of [18F]poly (ADP-ribose) polymerase inhibitor PET/MR

…, S Kossatz, EM Burnazi, S Roberts… - Neuro-Oncology …, 2020 - academic.oup.com
Background We report preclinical and first-in-human-brain-cancer data using a targeted poly
(ADP-ribose) polymerase 1 (PARP1) binding PET tracer, [ 18 F]PARPi, as a diagnostic tool …