User profiles for Sherko Kümmel

Sherko Kümmel

Professor für Medizin, Kliniken Essen-Mitte, Wissenschaftlicher Mitarbeiter Charité Berlin
Verified email at kem-med.com
Cited by 24470

[HTML][HTML] AGO recommendations for the surgical therapy of the axilla after neoadjuvant chemotherapy: 2021 update

…, J Heil, J Huober, HH Kreipe, S Kümmel… - Geburtshilfe und …, 2021 - thieme-connect.com
Über viele Jahrzehnte war die komplette Ausräumung der axillären Lymphknoten im Sinne
einer Axilladissektion ein Standardverfahren in der Therapie des Mammakarzinom. Die …

[HTML][HTML] Event-free survival with pembrolizumab in early triple-negative breast cancer

…, L Pusztai, H McArthur, S Kümmel… - … England Journal of …, 2022 - Mass Medical Soc
Background The addition of pembrolizumab to neoadjuvant chemotherapy led to a
significantly higher percentage of patients with early triple-negative breast cancer having a …

[HTML][HTML] Pembrolizumab for early triple-negative breast cancer

…, L Pusztai, H McArthur, S Kümmel… - … England Journal of …, 2020 - Mass Medical Soc
Background Previous trials showed promising antitumor activity and an acceptable safety
profile associated with pembrolizumab in patients with early triple-negative breast cancer. …

[HTML][HTML] AGO recommendations for the surgical therapy of breast cancer: update 2022

…, E Fallenberg, M Friedrich, S Kümmel… - Geburtshilfe und …, 2022 - thieme-connect.com
Die Empfehlungen der AGO Kommission Mamma zur operativen Therapie des Mammakarzinoms
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …

AGO-Empfehlungen zur operativen Therapie des Mammakarzinoms: Update 2022

…, E Fallenberg, M Friedrich, S Kümmel… - Senologie-Zeitschrift …, 2023 - thieme-connect.com
Die Empfehlungen der AGO-Kommission Mamma zur operativen Therapie des Mammakarzinoms
wurden zuletzt im März 2022 aktualisiert (www.ago-online.de). Da die operative …

Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy

…, JU Blohmer, T Karn, BM Pfitzner, S Kümmel… - The lancet …, 2018 - thelancet.com
Background Tumour-infiltrating lymphocytes (TILs) are predictive for response to neoadjuvant
chemotherapy in triple-negative breast cancer (TNBC) and HER2-positive breast cancer, …

Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial

…, S Paepke, B Gerber, DM Zahm, S Kümmel… - The lancet …, 2014 - thelancet.com
Background Preclinical data suggest that triple-negative breast cancers are sensitive to
interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, …

[PDF][PDF] Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and …

…, K Krappmann, M Schmidt, H Tesch, S Kümmel… - J Clin oncol, 2015 - academia.edu
Purpose Modulation of immunologic interactions in cancer tissue is a promising therapeutic
strategy. To investigate the immunogenicity of human epidermal growth factor receptor 2 (…

Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo …

…, M Kotliar, I Kudaba, S Kümmel… - The Lancet …, 2020 - thelancet.com
Background CLEOPATRA was a phase 3 study comparing the efficacy and safety of pertuzumab,
trastuzumab, and docetaxel with placebo, trastuzumab, and docetaxel in patients with …

[HTML][HTML] A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer …

…, WD Schmitt, G von Minckwitz, J Thomalla, S Kümmel… - Annals of …, 2019 - Elsevier
Background Combining immune-checkpoint inhibitors with chemotherapy yielded an
increased response rates in patients with metastatic triple-negative breast cancer (TNBC). …