[HTML][HTML] ELIXYS-a fully automated, three-reactor high-pressure radiosynthesizer for development and routine production of diverse PET tracers
Background Automated radiosynthesizers are vital for routine production of positron-emission
tomography tracers to minimize radiation exposure to operators and to ensure …
tomography tracers to minimize radiation exposure to operators and to ensure …
[HTML][HTML] Simplified programming and control of automated radiosynthesizers through unit operations
Background Many automated radiosynthesizers for producing positron emission tomography
(PET) probes provide a means for the operator to create custom synthesis programs. The …
(PET) probes provide a means for the operator to create custom synthesis programs. The …
[HTML][HTML] The b subunits in the peripheral stalk of F1F0 ATP synthase preferentially adopt an offset relationship
SB Claggett, MON Plancher, SD Dunn… - Journal of biological …, 2009 - ASBMB
The peripheral stalk of F 1 F 0 ATP synthase is essential for the binding of F 1 to F O and for
proper transfer of energy between the two sectors of the enzyme. The peripheral stalk of …
proper transfer of energy between the two sectors of the enzyme. The peripheral stalk of …
Functional Incorporation of Chimeric b Subunits into F1Fo ATP Synthase
SB Claggett, TB Grabar, SD Dunn… - Journal of …, 2007 - Am Soc Microbiol
F 1 F o ATP synthases function by a rotary mechanism. The enzyme's peripheral stalk serves
as the stator that holds the F 1 sector and its catalytic sites against the movement of the rotor…
as the stator that holds the F 1 sector and its catalytic sites against the movement of the rotor…
Manipulating the Length of the b Subunit F1 Binding Domain in F1F0 ATP Synthase from Escherichia coli
D Bhatt, SP Cole, TB Grabar, SB Claggett… - Journal of bioenergetics …, 2005 - Springer
The peripheral stalk of F 1 F 0 ATP synthase is composed of a parallel homodimer of b
subunits that extends across the cytoplasmic membrane in F 0 to the top of the F 1 sector. The …
subunits that extends across the cytoplasmic membrane in F 0 to the top of the F 1 sector. The …
ARC-P HS+: A versatile radiosynthesizer for the production of PET tracers
Objective: Positron Emission Tomography (PET) has seen dramatic growth in research over
the last 20 years, and is now a standard in the diagnosis, staging, and treatment monitoring …
the last 20 years, and is now a standard in the diagnosis, staging, and treatment monitoring …
The b arg36 contributes to efficient coupling in F1FO ATP synthase in Escherichia coli
AK Welch, SB Claggett, BD Cain - Journal of bioenergetics and …, 2008 - Springer
In Escherichia coli, the F 1 F O ATP synthase b subunits house a conserved arginine in the
tether domain at position 36 where the subunit emerges from the membrane. Previous …
tether domain at position 36 where the subunit emerges from the membrane. Previous …
A new paradigm for programming and controlling automated radiosynthesizers
1471 Objectives Software for radiochemistry systems has typically been designed with the
engineer rather than the radiochemist in mind, with programs for automated production of PET …
engineer rather than the radiochemist in mind, with programs for automated production of PET …
Diverse nucleophilic syntheses on the ELIXYS multi-pot, cassette-based radiosynthesizer
1484 Objectives In order to facilitate development of new PET probes, a means to safely and
routinely synthesize a wide variety of PET probes on a single platform is required. Methods …
routinely synthesize a wide variety of PET probes on a single platform is required. Methods …
Construction and disulfide crosslinking of chimeric b subunits in the peripheral stalk of F1FO ATP synthase from Escherichia coli
SB Claggett - 2008 - search.proquest.com
F1FO ATP synthases produce the majority of ATP consumed by living organisms by harnessing
the energy from oxidative phosphorylation and photosynthesis. These enzymes consist …
the energy from oxidative phosphorylation and photosynthesis. These enzymes consist …