Hypertension-associated hypalgesia: Evidence in experimental animals and humans, pathophysiological mechanisms, and potential clinical consequences

S Ghione - Hypertension, 1996 - Am Heart Assoc
A behavioral hypalgesia (increased response threshold to noxious stimuli) has been consistently,
although not invariably, reported in spontaneous and experimental acute and chronic …

Visceral fat in hypertension: influence on insulin resistance and β-cell function

…, D Ciociaro, V Postano, E Buzzigoli, S Ghione… - …, 2004 - Am Heart Assoc
Preferential visceral adipose tissue (VAT) deposition has been associated with the presence
of insulin resistance in obese and diabetic subjects. The independent association of VAT …

Arterial hypertension is associated with hypalgesia in humans.

S Ghione, C Rosa, L Mezzasalma, E Panattoni - Hypertension, 1988 - Am Heart Assoc
An association between increased blood pressure and hypalgesia has been reported in
several studies in animals and in a few reports in humans. We investigated the relationship …

Early hypertension is associated with reduced regional cardiac function, insulin resistance, epicardial, and visceral fat

AM Sironi, A Pingitore, S Ghione, D De Marchi… - …, 2008 - Am Heart Assoc
Mild-to-moderate hypertension is often associated with insulin resistance and visceral
adiposity. Whether these metabolic abnormalities have an independent impact on regional …

Microalbuminuria and casual and ambulatory blood pressure monitoring in normotensives and in patients with borderline and mild essential hypertension

…, L Palla, C Palombo, S Ghione - American Journal of …, 1989 - academic.oup.com
Several reports suggest that urinary albumin excretion may be elevated in patients with
essential hypertension and that this index may be a good predictor for cardiovascular …

Pain perception and electromagnetic fields

C Del Seppia, S Ghione, P Luschi… - Neuroscience & …, 2007 - Elsevier
A substantial body of evidence has accumulated showing that exposure to electromagnetic
fields (EMFs) affects pain sensitivity (nociception) and pain inhibition (analgesia). Consistent …

Perindopril and indapamide reverse coronary microvascular remodelling and improve flow in arterial hypertension

…, A Varela-Carver, M Mancini, S Ghione… - Journal of …, 2011 - journals.lww.com
Objectives Patients and animal models of arterial hypertension are characterized by
structural and functional abnormalities of the coronary microcirculation. Using a translational …

Seasonal influences on blood pressure in high normal to mild hypertensive range.

S Giaconi, S Ghione, C Palombo, A Genovesi-Ebert… - …, 1989 - Am Heart Assoc
To investigate the seasonal influences on various arterial blood pressure measurements, 22
subjects in the high normal to mild hypertensive range were examined twice following the …

Impaired insulin action on skeletal muscle metabolism in essential hypertension.

A Natali, D Santoro, C Palombo, M Cerri, S Ghione… - …, 1991 - Am Heart Assoc
Previous studies have shown that essential hypertension is frequently associated with insulin
resistance. The tissues responsible for this metabolic alteration have not been defined. We …

Effects of chronic angiotensin converting enzyme inhibition on glucose tolerance and insulin sensitivity in essential hypertension.

…, A Natali, C Palombo, LS Brandi, M Piatti, S Ghione… - …, 1992 - Am Heart Assoc
The relation between the renin-angiotensin-aldosterone (RAA) system and carbohydrate
metabolism and insulin sensitivity in essential hypertension has not been investigated …