To investigate frontal lobe white matter in children with autism spectrum disorder (ASD), we
performed diffusion tensor imaging (DTI) in 50 ASD children (mean age: 57.5 ± 29.2 months, …

Major frontal lobe tracts and corpus callosum (CC) were investigated in 32 children with
autism spectrum disorder (ASD, mean age: 5 years), 12 nonautistic developmentally impaired …

Background: Multiple rare copy number variants (CNVs) including genomic deletions and
duplications play a prominent role in neurodevelopmental disorders such as mental retardation…

The standardized uptake value (SUV) and the slope of the Patlak plot (K) have both been
proposed as indices to monitor the progress of disease during cancer therapy. Although a …

OBJECTIVE: To determine whether the major temporal lobe white matter tracts in patients
with temporal lobe epilepsy manifest abnormal water diffusion properties. METHODS: …

Ten members of a 3‐generation pedigree with 7 showing Tourette syndrome/chronic tic
phenotype (TS‐CTD) were evaluated with whole exome sequencing. We identified 3 novel, …

Angelman syndrome is a genetic disorder characterized by pervasive developmental
disability with failure to develop speech. We examined the basis for severe language delay in …

OBJECTIVE: To investigate cortical association tracts using diffusion tensor imaging (DTI) in
children with global developmental delay of unknown etiology. STUDY DESIGN: We …

BACKGROUND AND PURPOSE: Because we had previously observed geometric changes
of frontal lobe association pathways in children with ASD, in the present study we analyzed …

Background CYP2D6 plays a crucial role in drug metabolism of several drugs. It is known to
be highly polymorphic with enzymatic activity ranging from poor to ultrarapid metabolic rates…