User profiles for Selma Ugurel

Selma Ugurel

Professor of Medicine, University of Duisburg-Essen
Verified email at uk-essen.de
Cited by 16785

Melanoma

…, R Gutzmer, A Hauschild, A Stang, A Roesch, S Ugurel - The Lancet, 2018 - thelancet.com
Cutaneous melanoma causes 55 500 deaths annually. The incidence and mortality rates of
the disease differ widely across the globe depending on access to early detection and …

The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma

…, U Hillen, R Gutzmer, SM Goldinger, S Ugurel… - Cancer discovery, 2014 - AACR
Most patients with BRAF V600 -mutant metastatic melanoma develop resistance to selective
RAF kinase inhibitors. The spectrum of clinical genetic resistance mechanisms to RAF …

[HTML][HTML] Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

…, C Loquai, SM Goldinger, L Zimmer, S Ugurel… - European journal of …, 2016 - Elsevier
Selma Ugurel has received grants and travel support from Medac, personal fees from Roche
and MSD, and travel support from BMS. Ralf Gutzmer has received personal fees from BMS…

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

…, P Brafford, A Sucker, S Ugurel… - Pigment cell …, 2006 - Wiley Online Library
The molecular biology of metastatic potential in melanoma has been studied many times
previously and changes in the expression of many genes have been linked to metastatic …

[HTML][HTML] Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

…, SM Goldinger, L Hofmann, C Loquai, S Ugurel… - European journal of …, 2016 - Elsevier
Selma Ugurel has received grants and travel support from Medac, personal fees from Roche
and MSD, and travel support from BMS. Ioannis Thomas has received travel support from …

Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival

S Ugurel, G Rappl, W Tilgen… - Journal of clinical oncology, 2001 - ascopubs.org
PURPOSE: To determine the predictive value of the angiogenic serum factors angiogenin,
vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and …

[HTML][HTML] Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task

…, E Sody, N Steingrube, I Stoffels, S Ugurel… - European Journal of …, 2019 - Elsevier
Background Recent studies have successfully demonstrated the use of deep-learning
algorithms for dermatologist-level classification of suspicious lesions by the use of excessive …

[HTML][HTML] Survival of patients with advanced metastatic melanoma: the impact of novel therapies–update 2017

S Ugurel, J Röhmel, PA Ascierto, KT Flaherty… - European Journal of …, 2017 - Elsevier
The treatment of metastatic melanoma is still undergoing a process of major change. The
two most important novel therapeutic strategies, selective kinase inhibitors and immune …

[HTML][HTML] Superior skin cancer classification by the combination of human and artificial intelligence

…, G Lodde, S Sammet, W Sondermann, S Ugurel… - European Journal of …, 2019 - Elsevier
Background In recent studies, convolutional neural networks (CNNs) outperformed
dermatologists in distinguishing dermoscopic images of melanoma and nevi. In these studies, …

[HTML][HTML] A convolutional neural network trained with dermoscopic images performed on par with 145 dermatologists in a clinical melanoma image classification task

…, E Sody, N Steingrube, I Stoffels, S Ugurel… - European Journal of …, 2019 - Elsevier
Background Recent studies have demonstrated the use of convolutional neural networks (CNNs)
to classify images of melanoma with accuracies comparable to those achieved by …