Albumin-deficient rat mutant

S Nagase, K Shimamune, S Shumiya - Science, 1979 - science.org
An analbuminemic colony was established from Sprague-Dawley rats. Analbuminemia was
inherited as an autosomal recessive trait. The rates of growth and reproduction of the mutant …

[HTML][HTML] Lanosterol synthase mutations cause cholesterol deficiency–associated cataracts in the Shumiya cataract rat

…, T Serikawa, K Higuchi, S Shumiya - The Journal of …, 2006 - Am Soc Clin Investig
The Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous
occurrence of poorly differentiated epithelial cells at the bow area of the lens forms the …

[PDF][PDF] Evaluation of carbon-11-labeled KF17837: a potential CNS adenosine A2a receptor ligand

…, S Wakabayashi, T Nariai, S Shumiya… - Journal of Nuclear …, 1998 - Soc Nuclear Med
MATERIALS AND METHODS ('£ y)-8-(3, 4-dimethoxystyryl)-l, 3-dipropyl-7-methylxanthine
(KF17837) and (£> 8-(3, 4-dimethoxystyryl)-l, 3-dipropylxanthine, 8-(3-chlorostyryl) caffeine …

Albumin-deficient rat mutant: an animal model for analbuminemia

S NAGASE, K SHIMAMUNE, S SHUMIYA - Experimental Animals, 1980 - jstage.jst.go.jp
Total protein level of the serum in the mutant rat was similar to that of control Sprague-Dawley
rats and globulin increased compensatorily. Serum cholesterol concentration was …

Peptidases play an important role in cataractogenesis: an immunohistochemical study on lenses derived from Shumiya cataract rats

H Zhang, Y Yamamoto, S Shumiya… - The Histochemical …, 2001 - Springer
The role of proteolytic enzymes in Shumiya cataract rats in alterations to lens proteins
during cataract formation was studied immunohistochemically using antibodies against …

Establishment of the hereditary cataract rat strain (SCR) and genetic analysis.

S Shumiya - Laboratory Animal Science, 1995 - europepmc.org
The Shumiya cataract rat (SCR) and normal control rat strains of NC1 and NC2 were established.
Mean cataract appearance in adult SCR rats was 66.7%, and embryo death rate was …

Plasma lipid concentrations and enzyme activities in Nagase analbuminemia rats (NAR)

M TAKAHASHI, K KUSUMI, S SHUMIYA… - Experimental …, 1983 - jstage.jst.go.jp
Plasma lipid concentrations in NAR (Nagase Analbuminemia Rats) of 4 to 52 weeks old were
examined. Plasma enzymes of NAR were also measured in relation to liver function. The …

Involvement of inducible nitric oxide synthase in cataract formation in Shumiya cataract rat (SCR)

M Inomata, M Hayashi, S Shumiya… - Current Eye …, 2001 - Taylor & Francis
Purpose. Our previous results showed that the oral administration of aminoguanidine (AG),
an inhibitor of inducible nitric oxide synthase (iNOS), strongly suppresses lens opacification …

Histopathological study of hereditary cataractous lenses in SCR strain rat

T Okano, S Uga, S Ishikawa, S Shumiya - Experimental eye research, 1993 - Elsevier
A new cataractous rat strain, Shumiya Cataract Rat (SCR), which was derived from the cross-breeder
formed between the spontaneous hypertensive rat and the Zucker fatty rat, was …

[HTML][HTML] Evidence for the involvement of calpain in cataractogenesis in Shumiya cataract rat (SCR)

…, TC Saido, S Kawashima, S Shumiya - … et Biophysica Acta (BBA …, 1997 - Elsevier
The Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears
spontaneously in the nuclear and perinuclear portions at 11–12 weeks of age. It was found …