18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study
M Ogawa, S Ishino, T Mukai, D Asano… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The rupture of atherosclerotic plaques and the subsequent formation of thrombi are the
main factors responsible for myocardial and cerebral infarctions. Thus, the detection of …
main factors responsible for myocardial and cerebral infarctions. Thus, the detection of …
In vivo PET imaging of HDL in multiple atherosclerosis models
…, L Giesen, CH Wessel, J Witjes, S Ishino… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives : The goal of this study was to develop and validate a noninvasive imaging tool to
visualize the in vivo behavior of high-density lipoprotein (HDL) by using positron emission …
visualize the in vivo behavior of high-density lipoprotein (HDL) by using positron emission …
Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors
…, T Mukai, H Tamamura, T Mori, S Ishino… - Nuclear medicine and …, 2006 - Elsevier
The chemokine receptor CXCR4 is highly expressed in tumor cells and plays an important
role in tumor metastasis. The aim of this study was to develop a radiopharmaceutical for the …
role in tumor metastasis. The aim of this study was to develop a radiopharmaceutical for the …
Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques
…, Y Magata, T Kato, K Hatano, S Ishino… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The rupture of atherosclerotic vulnerable plaques and subsequent formation of thrombi are
the main factors responsible for myocardial and cerebral infarctions. Because macrophage …
the main factors responsible for myocardial and cerebral infarctions. Because macrophage …
Imaging macrophage and hematopoietic progenitor proliferation in atherosclerosis
Rationale: Local plaque macrophage proliferation and monocyte production in hematopoietic
organs promote progression of atherosclerosis. Therefore, noninvasive imaging of …
organs promote progression of atherosclerosis. Therefore, noninvasive imaging of …
Comparison of contrast agents for atherosclerosis imaging using cultured macrophages: FDG versus ultrasmall superparamagnetic iron oxide
T Satomi, M Ogawa, I Mori, S Ishino… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Various noninvasive imaging methods have been developed to evaluate atherosclerotic
plaques. Among them, 18 F-FDG PET and MR imaging with ultrasmall superparamagnetic iron …
plaques. Among them, 18 F-FDG PET and MR imaging with ultrasmall superparamagnetic iron …
Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability—analysis in hypercholesterolemic rabbits
S Ishino, T Mukai, N Kume, D Asano, M Ogawa, Y Kuge… - Atherosclerosis, 2007 - Elsevier
Lectin-like oxidized LDL receptor-1 (LOX-1), a cell-surface receptor for oxidized LDL (Ox-LDL),
has been implicated in vascular cell dysfunction related to atherosclerotic plaque …
has been implicated in vascular cell dysfunction related to atherosclerotic plaque …
Nanobody-facilitated multiparametric PET/MRI phenotyping of atherosclerosis
Objectives : This study sought to develop an integrative positron emission tomography (PET)
with magnetic resonance imaging (MRI) procedure for accurate atherosclerotic plaque …
with magnetic resonance imaging (MRI) procedure for accurate atherosclerotic plaque …
Targeting of lectinlike oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti–LOX-1 antibody: potential agent for imaging of vulnerable plaque
S Ishino, T Mukai, Y Kuge, N Kume… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Lectinlike oxidized low-density lipoprotein (LDL) receptor 1 (LOX-1), a cell surface receptor
for oxidized LDL, has been implicated in vascular cell dysfunction related to plaque instability…
for oxidized LDL, has been implicated in vascular cell dysfunction related to plaque instability…
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species
…, MMT van Leent, J Malkus, S Baxter, S Ishino… - Science translational …, 2019 - science.org
Nanomedicine research produces hundreds of studies every year, yet very few formulations
have been approved for clinical use. This is due in part to a reliance on murine studies, …
have been approved for clinical use. This is due in part to a reliance on murine studies, …