A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

…, D McNulty, MJ Blumenthal, JR Keys, SW Land Vatter… - Nature, 1994 - nature.com
Production of interleukin-1 and tumour necrosis factor from stimulated human monocytes is
inhibited by a new series of pyridinyl-imidazole compounds. Using radiolabelled and radio-…

[PDF][PDF] Preparation of four fluorine-18-labeled estrogens and their selective uptakes in target tissues of immature rats

DO Kiesewetter, MR Kilbourn, SW Landvatter… - J Nucl Med, 1984 - academia.edu
The measurement of the estrogen-receptor content of human breast tumors has proved useful
in selecting the most suitable form of treatment for metastatic disease: in general, tumors …

16 alpha-[77Br] bromo-11 beta-methoxyestradiol-17 beta: a gamma-emitting estrogen imaging agent with high uptake and retention by target organs.

…, SG Senderoff, KE Carlson, SW Landvatter… - Journal of nuclear …, 1982 - europepmc.org
16 alpha [77Br] Bromo-11 beta-methoxyestradiol-17 beta [MBE (Br-77)], a compound with
high affinity for the estrogen receptor and with low nonspecific binding, has been prepared …

Nonsteroidal estrogens: Synthesis and estrogen receptor binding affinity of derivatives of (3R*, 4S*)-3, 4-bis (4-hydroxyphenyl) hexane (hexestrol) and (2R*, 3S*)-2, 3 …

SW Landvatter… - Journal of Medicinal …, 1982 - ACS Publications
A series of nonsteroidal, side-chain functionalized estrogens based on (3fl*, 4S*)-3, 4-bis (4-hydroxyphenyl)
hexane (hexestrol) and (2f?*, 3S*)-2, 3-bis (4-hydroxyphenyl) pentane (…

(2R∗, 3S∗)-1-[18fluoro-2, 3-bis (4-hydroxyphenyl) pentane ([18F] fluoronorhexestrol), A positron-emitting estrogen that shows highly-selective, receptor-mediated …

SW Landvatter, DO Kiesewetter, MR Kilbourn… - Life sciences, 1983 - Elsevier
The positron-emitting, non-steroidal estrogen (2 R ∗ , 3 S ∗ )-1-[ 18 F]fluoro-2, 3-bis (4-hydroxyphenyl)
pentane ([ 18 F]-fluoronor-hexestrol), has been prepared by fluoride ion …

[PDF][PDF] Stereochemical considerations in the binding of nonsteroidal estrogens to the estrogen receptor

SW LANDVATTER, JA KATZENELLENBOGEN - Molecular Pharmacology, 1981 - Citeseer
LANDVATFER, SW, AND JA KATZENELLENBOGEN. Stereochemical considerations in the
binding of nonsteroidal estrogens to the estrogen receptor. Mol. Pharmacol. 20: 43-51 (1981)…

(2R*, 3S*)-1-[125I] Iodo-2, 3-bis (4-hydroxyphenyl) pentane ([125I] iodonorhexestrol), and (2R*, 3S*)-1-[77Br] bromo-2, 3-bis (4-hydroxyphenyl) pentane ([77Br] …

SW Landvatter, JA Katzenellenbogen… - Journal of Medicinal …, 1982 - ACS Publications
Two-emitting estrogen analogues,(2ņ*, 3S*)-l-[125I] iodo-2, 3-bis (4-hydroxyphenyl) pentane
([126I] iodonorhexestrol) and (2R*, 3S*)-l-[77Br] bromo-2, 3-bis (4-hydroxyphenyl) pentane (…

Oxohexestrol derivatives labeled with fluorine-18. Synthesis, receptor binding and in vivo distribution of two non-steroidal estrogens as potential breast tumor imaging …

KE Bergmann, SW Landvatter, PG Rocque… - Nuclear medicine and …, 1994 - Elsevier
We have prepared two non-steroidal estrogens in the 2-oxohexestrol series labeled with the
positron-emitting radionuclide fluorine-18, 1-fluoro-5-oxohexestrol (4) and 1-fluoro-2-…

Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin αIIbβ3: Evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and …

…, J Samanen, D Bennett, SW Landvatter, W Chen… - … of Pharmacology and …, 1998 - ASPET
The aggregation of activated platelets is mediated by the binding of fibrinogen to its cell surface
receptor, the integrin α IIb β 3 . The recognition of fibrinogen by α IIb β 3 depends, in part, …

Preparation and purification of 125I‐labeled iodospiroperidol

SW Landvatter - Journal of Labelled Compounds and …, 1985 - Wiley Online Library
Iodine‐125 labeled spiroperidol has been synthesized by a simple, one‐step procedure
starting from spiroperidol. This synthesis employs 125 I‐ and H 2 O 2 in buffered acetic acid. …