User profiles for Sarah Cuddy

Sarah Cuddy

Brigham and Women's Hospital
Verified email at bwh.harvard.edu
Cited by 941

Prognostic value of cardiac magnetic resonance tissue characterization in risk stratifying patients with suspected myocarditis

…, VL Murthy, V Agarwal, K Kaneko, S Cuddy… - Journal of the American …, 2017 - jacc.org
Background : Diagnosing myocarditis is challenged by nonspecific clinical signs and
symptoms and low accuracy of endomyocardial biopsy. Cardiac magnetic resonance imaging (…

How to image cardiac amyloidosis: a practical approach

S Dorbala, S Cuddy, RH Falk - Cardiovascular Imaging, 2020 - jacc.org
Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with
a median survival from diagnosis, if untreated, ranging from <6 months for light chain …

Effect of tafamidis on global longitudinal strain and myocardial work in transthyretin cardiac amyloidosis

GT Giblin, SAM Cuddy… - European Heart …, 2022 - academic.oup.com
Aims In patients with transthyretin amyloid cardiomyopathy (ATTR-CM), the effect of tafamidis
on myocardial function using serial speckle tracking echocardiography has not been …

Absolute quantitation of cardiac 99mTc-pyrophosphate using cadmium-zinc-telluride–based SPECT/CT

S Dorbala, MA Park, S Cuddy, V Singh… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The primary aims of this study were to determine the correlation between absolute quantitative
99m Tc-pyrophosphate metrics and traditional measures of cardiac amyloid burden and …

Improved quantification of cardiac amyloid burden in systemic light chain amyloidosis: redefining early disease?

SAM Cuddy, PE Bravo, RH Falk, S El-Sady… - Cardiovascular …, 2020 - jacc.org
Objectives The purpose of this study was to determine phenotypes characterizing cardiac
involvement in AL amyloidosis by using direct (fluorine-18-labeled florbetapir {[ 18 F]florbetapir…

99mTc Bone-Avid Tracer Cardiac Scintigraphy: Role in Noninvasive Diagnosis of Transthyretin Cardiac Amyloidosis

YM Khor, SAM Cuddy, V Singh, RH Falk, MF Di Carli… - Radiology, 2022 - pubs.rsna.org
Transthyretin cardiac amyloidosis (ATTR-CA) is an overlooked cause of heart failure, with
substantial morbidity and mortality. The emergence of several novel therapies has fueled the …

Amyloidosis as a systemic disease in context

SAM Cuddy, RH Falk - Canadian Journal of Cardiology, 2020 - Elsevier
The systemic amyloidoses are a group of diseases characterized by the deposition of amyloid,
a material formed from misfolding of proteins, in one or more organs. The 2 commonest …

Left atrial structure and function of the amyloidogenic V122I transthyretin variant in elderly African Americans

…, RM Inciardi, B Claggett, SAM Cuddy… - European Journal of …, 2021 - Wiley Online Library
Aims African‐American carriers of the transthyretin (TTR) valine‐to‐isoleucine substitution (V122I)
are at increased risk of heart failure, yet many have relatively subtle abnormalities of …

Cardiac magnetic resonance biomarkers as surrogate endpoints in cardiovascular trials for myocardial diseases

…, B Heydari, MC Gissler, Y Ge, SAM Cuddy… - European heart …, 2023 - academic.oup.com
Cardiac magnetic resonance offers multiple facets in the diagnosis, risk stratification, and
management of patients with myocardial diseases. Particularly, its feature to precisely monitor …

Cardiac Amyloid Quantification Using 124I-Evuzamitide (124I-P5+14) Versus 18F-Florbetapir: A Pilot PET/CT Study

OF Clerc, SAM Cuddy, M Robertson… - Cardiovascular …, 2023 - jacc.org
Background Cardiac amyloid quantification could advance early diagnosis of amyloid
cardiomyopathy (CMP) and treatment monitoring. However, current imaging tools are based on …