PET of poly (ADP-ribose) polymerase activity in cancer: preclinical assessment and first in-human studies

LS Michel, S Dyroff, FJ Brooks, KJ Spayd, S Lim… - Radiology, 2017 - pubs.rsna.org
Purpose To demonstrate that positron emission tomography (PET) with fluorine 18 ( 18 F)
fluorthanatrace (FTT) depicts activated poly (adenosine diphosphate–ribose)polymerase (…

Limited usefulness of classic MR findings in the diagnosis of tenosynovial giant cell tumor

J Crim, SL Dyroff, JD Stensby, A Evenski, LJ Layfield - Skeletal Radiology, 2021 - Springer
Objective To determine the frequency with which MRI of tenosynovial giant cell tumor
demonstrates hemosiderin, visible intralesional fat signal, and proximity to synovial tissue. Material …

The effects of the glycation of transferrin on chromium binding and the transport and distribution of chromium in vivo

G Deng, SL Dyroff, M Lockart, MK Bowman… - Journal of inorganic …, 2016 - Elsevier
Chromium (III) has been shown to act as a pharmacological agent improving insulin sensitivity
in rodent models of obesity, insulin resistance, and diabetes. To act in beneficial fashion, …

Angiosarcoma arising in massive localized lymphedema

S Dyroff, LJ Layfield, J Crim - Skeletal radiology, 2020 - Springer
We report a case of a 70-year-old woman with a BMI of 58 who developed cellulitis
refractory to treatment, within an area of massive localized lymphedema. Biopsy showed …

First-in-human studies characterizing a poly (ADP-ribose) polymerase (PARP) targeted tracer, 18F-FluorThanatrace (18F-FTT) for cancer imaging

D Chen, S Dyroff, L Michel, A Wang-Gillam, B Tan… - 2016 - Soc Nuclear Med
582 Objectives Poly(ADP-ribose)polymerase (PARP) inhibitors are an emerging therapeutic
class of anticancer drugs with the potential to treat cancers that are deficient in DNA repair …

Erratum: PET of poly (ADP-Ribose) polymerase activity in cancer: Preclinical assessment and first in-human studies (Radiology (2017) 282: 2 (453-463

LS Michel, S Dyroff, FJ Brooks, KJ Spayd, S Lim… - …, 2019 - profiles.wustl.edu
This erratum corrects an error in the original interpretation of the images from the two pancreatic
cancer cases reported in the manuscript. 18F-FluorThanaTrace (18F-FTT) images from …

Trivalent Chromium has no Effect on Delaying Azoxymethane-Induced Colorectal Cancer in FVB/NJ Mice

…, G Deng, MK Kuykendall, AM Tadros, SL Dyroff… - Biological trace element …, 2015 - Springer
As Cr(III) compounds have been shown to increase insulin sensitivity and decrease plasma
cholesterol and triglycerides in rodent models of diabetes and insulin resistance and as …

Weight intervention in endometrial cancer: A pilot program

…, ER Tuller, S Dyroff… - Gynecologic …, 2019 - gynecologiconcology-online.net
Objective: Obesity is a strong risk factor for the development and persistence of endometrial
cancer. Few patients receive direct physician-to-patient nutrition counseling in oncology. …

Glycation of transferrin affects chromium binding and transport

JB Vincent, G Deng, SL Dyroff - The FASEB Journal, 2016 - Wiley Online Library
Chromium, as the trivalent ion, can act as a pharmaceutical agent, increasing the sensitivity
of the body to insulin and improving the symptoms of conditions, such as type 2 diabetes, …

[HTML][HTML] Post-mastectomy benign lymphangioendothelioma of the skin following chronic lymphedema for breast carcinoma: a teaching case mimicking low-grade …

S Yamada, Y Yamada, M Kobayashi, R Hino… - Diagnostic …, 2014 - Springer
Benign lymphangioendothelioma (BL) represents a very rare lymphatic vascular proliferation.
Our aim is to be aware that owing to its characteristic features, pathologists can easily …