Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2, 5-dimethoxybenzyl)-2-phenoxyaniline
…, RM Baldwin, P Zhao, S Guleryuz… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Translocator protein (TSPO), also referred to as peripheral benzodiazepine receptor (PBR),
is a crucial 18-kDa outer mitochondrial membrane protein involved in numerous cellular …
is a crucial 18-kDa outer mitochondrial membrane protein involved in numerous cellular …
18FDG-PET Predicts Pharmacodynamic Response to OSI-906, a Dual IGF-1R/IR Inhibitor, in Preclinical Mouse Models of Lung Cancer
ET McKinley, JE Bugaj, P Zhao, S Guleryuz… - Clinical Cancer …, 2011 - AACR
Purpose: To evaluate 2-deoxy-2-[ 18 F]fluoro-d-glucose positron emission tomography
imaging ( 18 FDG-PET) as a predictive, noninvasive, pharmacodynamic (PD) biomarker of …
imaging ( 18 FDG-PET) as a predictive, noninvasive, pharmacodynamic (PD) biomarker of …
[HTML][HTML] Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions
…, S Kim, RJ Pyron, SB Pitts, S Guleryuz… - Journal of Biological …, 2023 - ASBMB
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (RTK) commonly
targeted for inhibition by anticancer therapeutics. Current therapeutics target EGFR's kinase …
targeted for inhibition by anticancer therapeutics. Current therapeutics target EGFR's kinase …
[HTML][HTML] Molecular imaging metrics to evaluate response to preclinical therapeutic regimens
RA Smith, S Guleryuz, HC Manning - Frontiers in bioscience: a …, 2011 - ncbi.nlm.nih.gov
Molecular imaging comprises a range of techniques, spanning not only several imaging
modalities but also many disease states and organ sites. While advances in new technology …
modalities but also many disease states and organ sites. While advances in new technology …
Thymidine salvage to reflect tumor cell proliferation: Implications for 18F-FLT PET as a biomarker in oncology
E McKinley, S Guleryuz, P Zhao, A Fu, N Mutic… - 2010 - Soc Nuclear Med
446 Objectives The PET tracer 3’-deoxy-3’[ 18 F]-fluorothymidine ( 18 F-FLT) potentially serves
as a biomarker of proliferation by reporting utilization of thymidine salvage via thymidine …
as a biomarker of proliferation by reporting utilization of thymidine salvage via thymidine …
Preclinical evaluation of TSPO ligand [18F] PBR06 for PET imaging of glioma
J Buck, E McKinley, M Hight, S Guleryuz, P Zhao, A Fu… - 2010 - Soc Nuclear Med
279 Objectives Translocator protein (TSPO), formerly known as the peripheral-type
benzodiazepine receptor (PBR), is a crucial trans-mitochondrial membrane protein involved in …
benzodiazepine receptor (PBR), is a crucial trans-mitochondrial membrane protein involved in …
FLT PET in colorectal cancer
ET McKinley - 2013 - ir.vanderbilt.edu
Biomarkers that predict response to targeted therapy in oncology are an essential component
of personalized medicine. With an increasing reliance on molecularly targeted therapies, …
of personalized medicine. With an increasing reliance on molecularly targeted therapies, …
[BOOK][B] FLT PET imaging in colorectal cancer
ET McKinley - 2013 - search.proquest.com
Current imaging criteria for evaluating therapeutic response are based upon anatomical
information according to Response Evaluation Criteria in Solid Tumors (RECIST) guidelines (1). …
information according to Response Evaluation Criteria in Solid Tumors (RECIST) guidelines (1). …
Use of 18FDG-PET imaging to predict treatment response to IGF-1R/IR targeted therapy in lung cancer
ET McKinley - 2011 - ir.vanderbilt.edu
… I am greatly indebted to all those who have helped me obtain results in this study especially
Ping Zhao, Saffet Guleryuz, Joe Bugaj, Praffula Gokhale, Christine Mantis, and everyone …
Ping Zhao, Saffet Guleryuz, Joe Bugaj, Praffula Gokhale, Christine Mantis, and everyone …
Unstable Middle Phalanx Base Fractures Treated With an Internal Joint Stabilizer: Preliminary Results
DM Klein, DE Teytelbaum, JS Patel, TE Combs… - HAND, 2023 - journals.sagepub.com
Background: Unstable fractures of the base of the middle phalanx are notorious for causing
chronic loss of proximal interphalangeal (PIP) joint function, and they remain a challenge for …
chronic loss of proximal interphalangeal (PIP) joint function, and they remain a challenge for …