PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells
…, AT Sane, C Garofalo, É Grenier, L Emonnot, S Yara… - Atherosclerosis, 2013 - Elsevier
OBJECTIVES: The proprotein convertase subtillisin/kexin type 9 (PCSK9) regulates cholesterol
metabolism via degradation of low-density lipoprotein receptor (LDLr). Although PCSK9 …
metabolism via degradation of low-density lipoprotein receptor (LDLr). Although PCSK9 …
Oxidative stress and DNA methylation regulation in the metabolic syndrome
S Yara, JC Lavoie, E Levy - Epigenomics, 2015 - Future Medicine
DNA methylation is implicated in tissue-specific gene expression and genomic imprinting. It
is modulated by environmental factors, especially nutrition. Modified DNA methylation …
is modulated by environmental factors, especially nutrition. Modified DNA methylation …
[HTML][HTML] Iron-ascorbate-mediated lipid peroxidation causes epigenetic changes in the antioxidant defense in intestinal epithelial cells: impact on inflammation
S Yara, JC Lavoie, JF Beaulieu, E Delvin, D Amre… - PloS one, 2013 - journals.plos.org
Introduction The gastrointestinal tract is frequently exposed to noxious stimuli that may cause
oxidative stress, inflammation and injury. Intraluminal pro-oxidants from ingested nutrients …
oxidative stress, inflammation and injury. Intraluminal pro-oxidants from ingested nutrients …
Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with …
…, P Gestraud, A Hamza, A Jacquet, M Jimenez, S Yara… - Lung Cancer, 2022 - Elsevier
Introduction Lung cancer remains the most frequent cause of brain metastases (BMs) and is
responsible for high morbidity and mortality. Intracranial response to systemic treatments is …
responsible for high morbidity and mortality. Intracranial response to systemic treatments is …
Brain 18F-FDG PET metabolic abnormalities in patients with long-lasting macrophagic myofascitis
…, E Guedj, J Aouizerate, S Yara… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The aim of this study was to characterize brain metabolic abnormalities in patients with
macrophagic myofascitis (MMF) and the relationship with cognitive dysfunction through the use of …
macrophagic myofascitis (MMF) and the relationship with cognitive dysfunction through the use of …
[HTML][HTML] Total parenteral nutrition induces sustained hypomethylation of DNA in newborn guinea pigs
S Yara, E Levy, W Elremaly, T Rouleau, JC Lavoie - Pediatric Research, 2013 - nature.com
Background: Neonatal total parenteral nutrition (TPN) is associated with animals with low
glucose tolerance, body weight, and physical activity at adulthood. The early life origin of adult …
glucose tolerance, body weight, and physical activity at adulthood. The early life origin of adult …
Abstract OT1-01-01: A randomised phase II trial of palbociclib and fulvestrant vs standard endocrine therapy in patients with ER positive HER2 negative breast cancer …
…, AF Okines, C Palmieri, P Schmid, C Swift, S Yara… - Cancer Research, 2023 - AACR
Background: Most patients with early stage oestrogen receptor positive (ER+) and HER2
negative breast cancer will be cured of their cancer. However, up to 20% of patients may …
negative breast cancer will be cured of their cancer. However, up to 20% of patients may …
Inhibition of the Hepatic DNA Methyltransferase by Peroxides Contaminating the Neonatal Parenteral Nutrition
S Yara, W Elremaly, T Rouleau, E Levy… - Free Radical Biology …, 2011 - academia.edu
Methods: At three days of age, a catheter is fixed in jugular of guinea pigs. Three groups
were used: 1) Control: animals enterally fed with regular chow; 2) PN: animals fed exclusively …
were used: 1) Control: animals enterally fed with regular chow; 2) PN: animals fed exclusively …
Brain pet metabolic abnormalities in patients with long-lasting macrophagic myofasciitis
…, J Aouizerate, E Guedj, R Gherardi, S Yara… - Morphologie, 2016 - Elsevier
Background Macrophagic myofasciitis (MMF) is characterized by abnormal long-term
persistence of aluminum hydroxide within macrophages at the site of previous immunization. …
persistence of aluminum hydroxide within macrophages at the site of previous immunization. …
[CITATION][C] Nrf2 Silencing Induces Oxidative Stress, Inflammation and Mitochondrial Dysfunctions in the Intestine
S Yara, R Taha, V Marcil, JF Beaulieu… - Free Radical Biology …, 2011 - infona.pl
… Sabrina Yara, Rame Taha, Valérie Marcil, Jean-Francois Beaulieu, Francois Boudreau,
Fernand-Pierre Gendron, Jean-Claude Lavoie, Ernie Seidman, Emile Levy …
Fernand-Pierre Gendron, Jean-Claude Lavoie, Ernie Seidman, Emile Levy …