User profiles for Sabina Eigenbrod
 | sabina eigenbrodVerified email at munich-business-school.de Cited by 3554 |
Quantifying prion disease penetrance using large population control cohorts
…, C Ponto, I Zerr, TFJ Kraus, S Eigenbrod… - Science translational …, 2016 - science.org
More than 100,000 genetic variants are reported to cause Mendelian disease in humans,
but the penetrance—the probability that a carrier of the purported disease-causing genotype …
but the penetrance—the probability that a carrier of the purported disease-causing genotype …
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
J Felsberg, N Thon, S Eigenbrod… - … journal of cancer, 2011 - Wiley Online Library
Epigenetic silencing of the O 6 ‐methylguanine‐DNA methyltransferase (MGMT) gene
promoter is associated with prolonged survival in glioblastoma patients treated with …
promoter is associated with prolonged survival in glioblastoma patients treated with …
Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM
…, J Linn, H Kretzschmar, H Janssen, S Eigenbrod… - Neurology, 2015 - AAN Enterprises
Objective: The aim of this prospective longitudinal study was to identify static and dynamic O-(2-[
18 F]fluoroethyl)-l-tyrosine PET ( 18 FET-PET)-derived imaging biomarkers in patients …
18 F]fluoroethyl)-l-tyrosine PET ( 18 FET-PET)-derived imaging biomarkers in patients …
MRI-suspected low-grade glioma: is there a need to perform dynamic FET PET?
…, B Suchorska, J Lutz, S Eigenbrod… - European journal of …, 2012 - Springer
Purpose Since differentiation between low-grade glioma (LGG) and high-grade glioma (HGG)
remains challenging according to MRI criteria alone, we investigated the discriminative …
remains challenging according to MRI criteria alone, we investigated the discriminative …
Low values of 5‐hydroxymethylcytosine (5hmC), the “sixth base,” are associated with anaplasia in human brain tumors
…, D Globisch, M Wagner, S Eigenbrod… - … Journal of Cancer, 2012 - Wiley Online Library
5‐Methylcytosine (5mC) in genomic DNA has important epigenetic functions in embryonic
development and tumor biology. 5‐Hydroxymethylcytosine (5hmC) is generated from 5mC by …
development and tumor biology. 5‐Hydroxymethylcytosine (5hmC) is generated from 5mC by …
Prognostic significance of dynamic 18F-FET PET in newly diagnosed astrocytic high-grade glioma
…, A Todica, S Eigenbrod… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Despite advances in diagnosis and the use of different therapeutic regimens in astrocytic
high-grade glioma (HGG), the prognosis for patients remains grim. Additional pretherapeutic …
high-grade glioma (HGG), the prognosis for patients remains grim. Additional pretherapeutic …
Dynamic 18F-FET PET in newly diagnosed astrocytic low-grade glioma identifies high-risk patients
…, B Suchorska, V Wenter, S Eigenbrod… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Because the clinical course of low-grade gliomas in the individual adult patient varies
considerably and is unpredictable, we investigated the prognostic value of dynamic 18 F-…
considerably and is unpredictable, we investigated the prognostic value of dynamic 18 F-…
[HTML][HTML] Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice
A Pfeifer, S Eigenbrod, S Al-Khadra… - The Journal of …, 2006 - Am Soc Clin Investig
Prion diseases are fatal neurodegenerative diseases characterized by the accumulation of
PrP Sc , the infectious and protease-resistant form of the cellular prion protein (PrP C ). We …
PrP Sc , the infectious and protease-resistant form of the cellular prion protein (PrP C ). We …
[HTML][HTML] O6-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation
Background We analyzed prospectively whether MGMT (O 6 -methylguanine-DNA
methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT …
methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT …
Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [18F]FET-PET imaging in intracranial WHO grade II and III gliomas
NL Jansen, C Schwartz, V Graute, S Eigenbrod… - Neuro …, 2012 - academic.oup.com
Oligodendroglial components (OC) and loss of heterozygosity on chromosomes 1p and 19q
(LOH 1p/19q) are associated with better outcome in patients with glioma. We aimed to …
(LOH 1p/19q) are associated with better outcome in patients with glioma. We aimed to …