Familial adenomatous polyposis coli (FAP) is a disease characterized by the development
of multiple colorectal adenomas, and affected individuals carry germline mutations in the …

PRION protein (PrP) is a glycoprotein constitutively expressed on the neuronal cell surface.
A protease-resistant isoform of prion protein is implicated in the pathogenesis of a series of …

Synovial sarcoma ( SS ) is a rare yet refractory soft‐tissue sarcoma that predominantly
affects young adults. We show in a mouse model that radioimmunotherapy ( RIT ) with an α‐…

Exposure to asbestos is a known etiological factor in malignant mesothelioma (MM). However,
in vitro cell culture studies have provided paradoxical evidence that asbestos exposure to …

Peritoneal metastasis of gastric cancer ( PMGC ) is incurable and thus has an extremely poor
prognosis. We have found, however, that locoregionally administered trastuzumab armed …

The cellular prion protein, designated PrP c , is a key molecule in the prion diseases but its
physiological function remains unknown. To elucidate whether PrP c plays some role in the …

Objective Programmed cell death-ligand 1 (PD-L1) is expressed in tumor cells and has been
shown to predict clinical outcomes of several types of malignancies. The aim of this study …

By screening cDNA expression libraries derived from fresh leukemic cells of adult T-cell
leukemia for the potential to transform murine fibroblasts, NIH3T3, we have identified a novel …

Apc is a gene associated with familial adenomatous polyposis coli (FAP) and its inactivation
is a critical step in colorectal tumor formation. The protein product, adenomatous polyposis …

Recently, 211 At has received increasing attention as a potential radionuclide for cancer
radioimmunotherapy. It is a α-particle emitter, which is extremely effective against malignant …