L EVIN ET AL in the early computed tomographic (CT)-scan era proposed response criteria
for patients with malignant (ie, anaplastic) glioma receiving chemotherapy.'These criteria …

Chemotherapy for brain tumours has been limited because of difficulty in achieving adequate
exposure to the tumour without systemic toxicity. We have developed a method for local …

PURPOSE: Primary CNS lymphoma (PCNSL) is an aggressive primary brain tumor. Cranial
irradiation alone rarely results in long-term disease control or prolonged survival. We …

✓ Malignant gliomas have been difficult to treat with chemotherapy. The most effective agent,
BCNU (carmustine), has considerable systemic toxicity and a short half-life in serum. To …

✓ Pathological findings in 20 cases of glioblastoma multiforme were correlated with clinical
histories and computerized tomographic (CT) scans. This was done to define the neoplasm …

The serum and cerebrospinal fluid (CSF) of 8 women with ataxia, 6 of whom also had eye
movement abnormalities believed to be opsoclonus, were found to contain a highly specific …

There have been a number of clinical reports suggesting an increasing incidence of primary
brain lymphoma unrelated to acquired immune deficiency syndrome (AIDS) and organ …

Pre- and postoperative computerized tomography scans, simulator films, and computerized
tomography scans documenting tumor recurrence were analyzed on 70 patients with …

PURPOSE Prior studies show that increased levels of the DNA repair protein O6
methylguanine-DNA methyltransferase (MGMT), also referred to as O6-alkylguanine-DNA …

RMP-7, a bradykinin analog, temporarily increases the permeability of the blood-brain tumor
barrier to chemotherapy drugs like carboplatin. We conducted a randomized, controlled trial …