Clinical translation of a click-labeled 18F-octreotate radioligand for imaging neuroendocrine tumors

…, A Saleem, M Huiban, R Janisch… - Journal of Nuclear …, 2016 - Soc Nuclear Med
We conducted the first-in-human study of 18 F-fluoroethyl triazole [Tyr 3 ] octreotate ( 18 F-FET-βAG-TOCA)
in patients with neuroendocrine tumors (NETs) to evaluate biodistribution, …

Role of 18F-fluorodeoxyglucose Positron Emission Tomography in the Monitoring of Inflammatory Activity in Crohn's Disease

EA Russo, S Khan, R Janisch, RN Gunn… - Inflammatory bowel …, 2016 - academic.oup.com
Background 18 Fluorine-fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET)
has recently attracted interest for the measurement of disease activity in Crohn's disease (…

Characterization of 3 PET tracers for quantification of mitochondrial and synaptic function in healthy human brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J

A Mansur, EA Rabiner, RA Comley… - Journal of Nuclear …, 2020 - Soc Nuclear Med
… We thank Elbert Perez, Ryan Janisch, and Mark Tanner for their expert assistance. We also
thank the Yale University PET Center for providing the centrum semiovale regional definition. …

SNMMI NEWSLINE

C Kratochwil, FL Giesel, M Stefanova, M Benešova… - Soc Nuclear Med
… Dubash, Nicholas Keat, Paola Mapelli, Frazer Twyman, Laurence Carroll, Kasia Kozlowski,
Adil Al-Nahhas, Azeem Saleem, Mickael Huiban, Ryan Janisch, Andrea Frilling, Rohini …

[HTML][HTML] Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease

Y Helo, GE Searle, F Borghese, S Abraham, A Saleem - EJNMMI research, 2020 - Springer
Objective Expression of the translocator protein (TSPO) on inflammatory cells has facilitated
imaging of synovitis with TSPO-targeted positron emission tomography (PET). We aimed to …

Test–retest variability and reference region-based quantification of 18F-BCPP-EF for imaging mitochondrial complex I in the human brain

A Mansur, EA Rabiner, H Tsukada… - Journal of Cerebral …, 2021 - journals.sagepub.com
Mitochondrial complex I (MC-I) is an essential regulator of brain bioenergetics and can be
quantified in the brain using PET radioligand 18 F-BCPP-EF. Here we evaluate the test–retest …

[HTML][HTML] Synaptic terminal density early in the course of schizophrenia: An in vivo UCB-J positron emission tomographic imaging study of SV2A

EC Onwordi, T Whitehurst, E Shatalina, A Mansur… - Biological …, 2024 - Elsevier
Background The synaptic hypothesis is an influential theory of the pathoetiology of
schizophrenia (SCZ), which is supported by the finding that there is lower uptake of the synaptic …

A phase I study of liposomal doxorubicin (Doxil) with topotecan

CW Ryan, GF Fleming, L Janisch… - American journal of …, 2000 - journals.lww.com
New therapies are needed for patients with advanced ovarian cancer who relapse after initial
treatment with platinum and/or paclitaxel-based regimens. This study sought to determine …

The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size

KM Janisch, VM Vock, MS Fleming, A Shrestha… - …, 2013 - journals.biologists.com
Mammalian neuroepithelial stem cells divide using a polarized form of cytokinesis, which is
not well understood. The cytokinetic furrow cleaves the cell by ingressing from basal to apical…

A phase I study of suramin with once-or twice-monthly dosing in patients with advanced cancer

CW Ryan, EE Vokes, NJ Vogelzang, L Janisch… - Cancer chemotherapy …, 2002 - Springer
Heading Abstract Purpose. The optimal schedule of administration of suramin has not been
well defined. The purpose of this study was to determine the maximum tolerated dose and …