U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging

…, B Vastenhouw, RM Ramakers… - Journal of Nuclear …, 2009 - Soc Nuclear Med
We present a new rodent SPECT system (U-SPECT-II) that enables molecular imaging of
murine organs down to resolutions of less than half a millimeter and high-resolution total-body …

VECTor: a preclinical imaging system for simultaneous submillimeter SPECT and PET

…, R Kreuger, RM Ramakers… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Today, PET and SPECT tracers cannot be imaged simultaneously at high resolutions but
require 2 separate imaging systems. This paper introduces a Versatile Emission Computed …

Quarter-Millimeter-Resolution Molecular Mouse Imaging with U-SPECT+

…, JL Villena, HC Groen, RM Ramakers… - Molecular …, 2015 - journals.sagepub.com
Limited spatial resolution of preclinical positron emission tomography (PET) and single-photon
emission computed tomography (SPECT) has slowed down applications of molecular …

Ultra-high-sensitivity submillimeter mouse SPECT

…, MC Goorden, RM Ramakers… - Journal of Nuclear …, 2015 - Soc Nuclear Med
SPECT with submegabecquerel amounts of tracer or subsecond time resolution would enable
a wide range of new imaging protocols such as screening tracers with initially low yield or …

Performance assessment of a preclinical PET scanner with pinhole collimation by comparison to a coincidence-based small-animal PET scanner

…, MC Goorden, K Dinelle, RM Ramakers… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET imaging of rodents is increasingly used in preclinical research, but its utility is limited by
spatial resolution and signal-to-noise ratio of the images. A recently developed preclinical …

Fast spiral SPECT with stationary γ-cameras and focusing pinholes

…, F van der Have, RM Ramakers… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Small-animal SPECT systems with stationary detectors and focusing multiple pinholes can
achieve excellent resolution–sensitivity trade-offs. These systems are able to perform fast total…

Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

…, AC Fluit, JM Kwiecinski, GC Krijger, RM Ramakers… - Elife, 2022 - elifesciences.org
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm
formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. …

Imaging of folate receptor expressing macrophages in the rat groove model of osteoarthritis: using a new DOTA-folate conjugate

…, NM Korthagen, C Müller, RM Ramakers… - Cartilage, 2018 - journals.sagepub.com
Objective To evaluate the presence and localization of folate receptor expressing macrophages
in the rat groove model of osteoarthritis and determine the suitability of a new folate …

High-resolution clustered pinhole 131Iodine SPECT imaging in mice

…, O Ivashchenko, MC Goorden, RM Ramakers… - Nuclear medicine and …, 2016 - Elsevier
Introduction High-resolution pre-clinical 131 I SPECT can facilitate development of new
radioiodine therapies for cancer. To this end, it is important to limit resolution-degrading effects of …

3-D rat brain phantom for high-resolution molecular imaging

…, J Booij, M Gerrits, C Ji, R Ramakers… - Proceedings of the …, 2009 - ieeexplore.ieee.org
With the steadily improving resolution of novel small-animal single photon emission
computed tomography (SPECT) and positron emission tomography devices, highly detailed …