User profiles for Romain Bejot
Romain Bejot, PhDIpsen Verified email at ipsen.com Cited by 640 |
Fluorous synthesis of 18F radiotracers with the [18F] fluoride ion: nucleophilic fluorination as the detagging process.
Tag team: The flouro-detagging of flourous sulfonates by the [ 18F]fluoride ion was found to
be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups …
be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups …
Batch‐mode microfluidic radiosynthesis of N‐succinimidyl‐4‐[18F]fluorobenzoate for protein labelling
R Bejot, AM Elizarov, E Ball, J Zhang… - Journal of Labelled …, 2011 - Wiley Online Library
The batch microfluidic technology is a promising system for sequential chemical steps combining
the advantages of micro‐scale reactions, while addressing some shortcomings of flow‐…
the advantages of micro‐scale reactions, while addressing some shortcomings of flow‐…
Convergent 18 F radiosynthesis: a new dimension for radiolabelling
The availability of radiolabelled probes is important for in vivo studies by positron emission
tomography (PET). Among the frontier challenges in 18F-radiochemistry are the …
tomography (PET). Among the frontier challenges in 18F-radiochemistry are the …
The traceless Staudinger ligation for indirect 18 F-radiolabelling
The Staudinger ligation of phosphine-substituted thioesters with 18F-fluoroethylazide has
been successfully applied to access 18F-labelled molecules in radiochemical yields …
been successfully applied to access 18F-labelled molecules in radiochemical yields …
A fluorous and click approach for screening potential PET probes: evaluation of potential hypoxia biomarkers
Radiopharmaceuticals for nuclear imaging are essentially targeting molecules, labeled with
short-lived radionuclides (eg, F-18 for PET). A significant drawback of radiopharmaceuticals …
short-lived radionuclides (eg, F-18 for PET). A significant drawback of radiopharmaceuticals …
Pre-clinical evaluation of a 3-nitro-1, 2, 4-triazole analogue of [18F] FMISO as hypoxia-selective tracer for PET
Hypoxia in solid tumours is associated with the promotion of various metabolic mechanisms
and induces resistance to radio- and chemotherapy. Non-invasive positron emission …
and induces resistance to radio- and chemotherapy. Non-invasive positron emission …
Stereoselective transformations of trihalomethylcarbinols induced by chromous chloride
R Bejot, S Tisserand, LM Reddy… - Angewandte Chemie …, 2005 - Wiley Online Library
(Z/E> 99: 1)[d] 12[f] 0 13 [g] 1k[f] 0 14[f] 0 [a] Yields for isolated materials after purification by
column chromatography, unless otherwise stated.[b] Yields calculated from 1H NMR …
column chromatography, unless otherwise stated.[b] Yields calculated from 1H NMR …
Fe (0)-mediated synthesis of tri-and tetra-substituted olefins from carbonyls: An environmentally friendly alternative to Cr (II)
JR Falck, R Bejot, DK Barma… - The Journal of …, 2006 - ACS Publications
Fe(0) was investigated as a cost-effective, environmentally friendly alternative to Cr(II) for the
olefination of carbonyls by activated polyhalides. In many instances, Fe(0) was equivalent …
olefination of carbonyls by activated polyhalides. In many instances, Fe(0) was equivalent …
[HTML][HTML] 177Lu-OPS201 targeting somatostatin receptors: in vivo biodistribution and dosimetry in a pig model
Background 177 Lu is used in peptide receptor radionuclide therapies for the treatment of
neuroendocrine tumors. Based on the recent literature, SST2 antagonists are superior to …
neuroendocrine tumors. Based on the recent literature, SST2 antagonists are superior to …
Ring Expansion/Homologation−Aldehyde Condensation Cascade Using tert-Trihalomethylcarbinols
Treatment of cyclic tert-trihalomethylcarbinols with CrCl 2 in THF/HMPA in the presence of
aryl or aliphatic aldehydes initiates a cascade sequence of one carbon ring expansion−…
aryl or aliphatic aldehydes initiates a cascade sequence of one carbon ring expansion−…