177Lu-AMBA: synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer
…, L Lattuada, KE Linder, RE Swenson… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Gastrin-releasing peptide receptors (GRP-R) are upregulated in many cancers, including
prostate, breast, and lung. We describe a new radiolabeled bombesin (BBN) analog for …
prostate, breast, and lung. We describe a new radiolabeled bombesin (BBN) analog for …
Effect of N-methyl substitution of the peptide bonds in luteinizing hormone-releasing hormone agonists
F Haviv, TD Fitzpatrick, RE Swenson… - Journal of medicinal …, 1993 - ACS Publications
Each peptide bond in leuprolide (1), deslorelin (13), and nafarelin (24) was separately
substituted with IV-methyl. The synthesized compounds were tested for in vitro receptor binding, …
substituted with IV-methyl. The synthesized compounds were tested for in vitro receptor binding, …
[HTML][HTML] Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4+ T cell apoptosis promoting HCC development
Hepatocellular carcinoma (HCC) is a common cause of cancer-related death worldwide. As
obesity and diabetes become more prevalent, the contribution of non-alcoholic fatty liver …
obesity and diabetes become more prevalent, the contribution of non-alcoholic fatty liver …
Order‐Unity 13C Nuclear Polarization of [1‐13C]Pyruvate in Seconds and the Interplay of Water and SABRE Enhancement
…, I Mandzhieva, J Ettedgui, RE Swenson… - …, 2022 - Wiley Online Library
Signal Amplification By Reversible Exchange in SHield Enabled Alignment Transfer (SABRE‐SHEATH)
is investigated to achieve rapid hyperpolarization of 13 C 1 spins of [1‐ 13 C]…
is investigated to achieve rapid hyperpolarization of 13 C 1 spins of [1‐ 13 C]…
Synthesis of Substituted Quinolines Using the Dianion Addition of N-Boc-anilines and α-Tolylsulfonyl-α,β-unsaturated Ketones
RE Swenson, TJ Sowin, HQ Zhang - The Journal of organic …, 2002 - ACS Publications
A short and versatile synthesis of substituted quinolines is provided. Alkylation of sodium
tolylsulfinate with bromomethyl- or chloromethyl ketones generates β-keto sulfones. …
tolylsulfinate with bromomethyl- or chloromethyl ketones generates β-keto sulfones. …
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity
…, A Thureau, F Allemand, RE Swenson… - Nature structural & …, 2023 - nature.com
Huntington’s disease is a neurodegenerative disorder caused by a CAG expansion in the
first exon of the HTT gene, resulting in an extended polyglutamine (poly-Q) tract in huntingtin (…
first exon of the HTT gene, resulting in an extended polyglutamine (poly-Q) tract in huntingtin (…
Rapid 13C Hyperpolarization of the TCA Cycle Intermediate α-Ketoglutarate via SABRE-SHEATH
…, D Sail, K Yamamoto, RE Swenson… - Analytical …, 2022 - ACS Publications
α-Ketoglutarate is a key biomolecule involved in a number of metabolic pathways─most
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with cancer. …
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with cancer. …
Immuno-PET imaging of the programmed cell death-1 ligand (PD-L1) using a zirconium-89 labeled therapeutic antibody, avelumab
…, D Butcher, EF Edmondson, RE Swenson… - Molecular …, 2019 - journals.sagepub.com
Objective: The goal is to evaluate avelumab, an anti-PD-L1 monoclonal immunoglobulin G
antibody labeled with zirconium-89 in human PD-L1-expressing cancer cells and mouse …
antibody labeled with zirconium-89 in human PD-L1-expressing cancer cells and mouse …
Novel synthesis of 19-nor-vitamin D compounds
KL Perlman, RE Swenson, HE Paaren, HK Schnoes… - Tetrahedron …, 1991 - Elsevier
Abstract 1α, 25-Dihydroxy-19-nor-vitamin D 3 was prepared efficiently in a convergent
synthesis starting with (−)-quinic acid and a ketone of the Windaus-Grundmann type.
synthesis starting with (−)-quinic acid and a ketone of the Windaus-Grundmann type.
Low-cost high-pressure clinical-scale 50% parahydrogen generator using liquid nitrogen at 77 K
…, C Meersman, J Ettedgui, RE Swenson… - Analytical …, 2021 - ACS Publications
We report on a robust and low-cost parahydrogen generator design employing liquid
nitrogen as a coolant. The core of the generator consists of catalyst-filled spiral copper tubing, …
nitrogen as a coolant. The core of the generator consists of catalyst-filled spiral copper tubing, …